Recombinant Human IFNA10 Protein, His-tagged

• Cat.No.: IFNA10-430H
• Product Overview: Recombinant Human IFNA10 (NP_002162.1) (Cys24-Asp189) was expressed with a polyhistidine tag at the C-terminus

Specification

• Description: Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymph centigradeytes; and they increase the ability of uninfected host cells to resist new infection by virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Human IFN are divided on the sequence of amino-acids into three groups: Alpha, Beta and Gamma interferons.
• Source: Yeast
• Species: Human
• Tag: His
• Predicted N Terminal: Cys 24
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant human IFNA10 consists of 176 amino acids and predicts a molecular mass of 20.8 kDa.
• Protein length: Cys24-Asp189
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: IFNA10 interferon, alpha 10 [ Homo sapiens ]
• Official Symbol: IFNA10
• Synonyms: IFNA10; interferon, alpha 10; interferon alpha-10; IFN alphaC; leIF C; IFN-alpha-10; interferon alpha-C; interferon alpha-6L; IFN-alphaC; MGC119878; MGC119879
• Gene ID: 3446
• mRNA Refseq: NM_002171
• Protein Refseq: NP_002162
• MIM: 147577
• UniProt ID: P01566