Recombinant Human IFNAR2 Protein, hIgG/His-tagged

• Cat.No.: IFNAR2-003H
• Product Overview: Recombinant Human IFNAR2 Protein (27-243aa) with hIgG/His tag was expressed in insect cells.

Specification

• Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45.
• Source: Insect Cells
• Species: Human
• Tag: hIgG/His
• Form: Liquid
• Molecular Mass: 51.7kDa (456aa)
• Protein length: 27-243aa
• AA Sequence: ISYDSPDYTDESCTFKISLRNFRSI LSWELKNHSIVPTHYTLLYTIMSKP EDLKVVKNCANTTRSFCDLTDEWRS THEAYVTVLEGFSGNTTLFSCSHNF WLAIDMSFEPPEFEIVGFTNHINVM VKFPSIVEEELQFDLSLVIEEQSEG IVKKHKPEIKGNMSGNFTYIIDKLI PNTNYCVSVYLEHSDEQAVIKSPLK CTLLPPGQESESAESAK
• Endotoxin: < 1 EU per 1 µg of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/mL (determined by Absorbance at 280nm)
• Storage Buffer: In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information

• Gene Name: IFNAR2 interferon alpha and beta receptor subunit 2 [ Homo sapiens (human) ]
• Official Symbol: IFNAR2
• Synonyms: IFNAR2; interferon alpha and beta receptor subunit 2; IFN-R; IMD45; IFNABR; IFNARB; IFN-alpha-REC; interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha/beta receptor 2; human interferon alpha/beta receptor; interferon (alpha, beta and omega) receptor 2; interferon alpha binding protein; interferon receptor; interferon-alpha/beta receptor beta chain; type I interferon receptor 2
• Gene ID: 3455
• mRNA Refseq: NM_207585
• Protein Refseq: NP_997468
• MIM: 602376
• UniProt ID: P48551