Recombinant Human IFNAR2 Protein, hIgG/His-tagged IFNAR2-003H

Recombinant Human IFNAR2 Protein, hIgG/His-tagged

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Recombinant Human IFNAR2 Protein, hIgG/His-tagged

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Cat.No. : IFNAR2-003H
Product Overview : Recombinant Human IFNAR2 Protein (27-243aa) with hIgG/His tag was expressed in insect cells.
Description : The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45.
Source : Insect Cells
Species : Human
Tag : hIgG/His
Form : Liquid
Molecular Mass : 51.7kDa (456aa)
Protein length : 27-243aa
AA Sequence : ISYDSPDYTD ESCTFKISLR NFRSILSWEL KNHSIVPTHY TLLYTIMSKP EDLKVVKNCA NTTRSFCDLT DEWRSTHEAY VTVLEGFSGN TTLFSCSHNF WLAIDMSFEP PEFEIVGFTN HINVMVKFPS IVEEELQFDL SLVIEEQSEG IVKKHKPEIK GNMSGNFTYI IDKLIPNTNY CVSVYLEHSD EQAVIKSPLK CTLLPPGQES ESAESAK<LE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH>
Endotoxin : < 1 EU per 1 µg of protein (determined by LAL method)
Purity : > 90% by SDS-PAGE
Applications : SDS-PAGE
Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/mL (determined by Absorbance at 280nm)
Storage Buffer : In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
SDS-PAGE :

3 µg by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Gene Name : IFNAR2 interferon alpha and beta receptor subunit 2 [ Homo sapiens (human) ]
Official Symbol : IFNAR2
Synonyms : IFNAR2; interferon alpha and beta receptor subunit 2; IFN-R; IMD45; IFNABR; IFNARB; IFN-alpha-REC; interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha/beta receptor 2; human interferon alpha/beta receptor; interferon (alpha, beta and omega) receptor 2; interferon alpha binding protein; interferon receptor; interferon-alpha/beta receptor beta chain; type I interferon receptor 2
Gene ID : 3455
mRNA Refseq : NM_207585
Protein Refseq : NP_997468
MIM : 602376
UniProt ID : P48551

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