Recombinant Human IFNGR2, GST-tagged

• Cat.No.: IFNGR2-14083H
• Product Overview: Recombinant Human IFNGR2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 125-324a.a.
• Description: This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) [ Homo sapiens ]
• Official Symbol: IFNGR2
• Synonyms: IFNGR2; interferon gamma receptor 2 (interferon gamma transducer 1); IFNGT1; interferon gamma receptor 2; AF 1; IFN-gamma-R2; IFN-gamma receptor 2; interferon gamma transducer 1; interferon gamma receptor beta chain; interferon gamma receptor accessory factor 1; interferon gamma receptor accessory factor-1; AF-1; IFGR2
• Gene ID: 3460
• mRNA Refseq: NM_005534
• Protein Refseq: NP_005525
• MIM: 147569
• UniProt ID: P38484
• Chromosome Location: 21q22.1
• Pathway: Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem
• Function: interferon-gamma receptor activity; receptor activity