Recombinant Human IFT74 Protein, His-tagged

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Recombinant Human IFT74 Protein, His-tagged

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Cat.No. : IFT74-1393H
Product Overview : Recombinant human IFT74 protein, fused to His tag at N-terminus, was expressed in E. coli.
Description : This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017]
Source : E. coli
Species : Human
Tag : His
Form : 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
Molecular Mass : 69.1 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : IFT74 intraflagellar transport 74 homolog (Chlamydomonas) [ Homo sapiens ]
Official Symbol : IFT74
Synonyms : BBS20; CCDC2; CMG-1; CMG1
Gene ID : 80173
mRNA Refseq : NM_001099222
Protein Refseq : NP_001092692
MIM : 608040
UniProt ID : Q96LB3

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