Recombinant Human IGFBP7 Protein (Ser27-Leu282), N-His-SUMO tagged, Animal-free, Carrier-free
Cat.No. : | IGFBP7-160H |
Product Overview : | Recombinant Human IGFBP7 Protein (Ser27-Leu282) with N-His-SUMO tag was expressed in HEK293 and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | IGFBP7, also known as mac25, prostacyclin-stimulating factor (PSF), tumor adhesion factor (TAF), and angiomodulin (AGM), is a secreted protein that belongs to the insulin-like growth factor (IGF)-binding protein (IGFBP) family. In contrast to the other family members, IGFBP7 binds IGFs through the N-terminal domain with low affinity. IGFBP7 is expressed in various human tissues, including the brain, liver, pancreas, and skeletal muscle, and is secreted into circulation. IGF-BP7 modulates many biological functions, such as protein synthesis, proliferation, anti-apoptosis, and cell survival. Moreover, it has been reported that IGFBP7 promotes cardiac senescence through IGF-1R/IRS/AKT-dependent suppression of FOXO3a, inhibiting DNA repair, subsequently the leading to the progression of Heart failure. Human and mouse IGFBP7 are highly homologous, sharing 94% a.a. sequence identity. |
Source : | HEK293 cell |
Species : | Human |
Tag : | N-His-SUMO |
Form : | Lyophilized |
Molecular Mass : | The protein has a calculated MW of 38.18 kDa. The protein migrates as 55 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Ser27-Leu282 |
Endotoxin : | < 1 EU/μg of the protein by the LAL method. |
Purity : | >95% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | IGFBP7 insulin-like growth factor binding protein 7 [ Homo sapiens (human) ] |
Official Symbol : | IGFBP7 |
Synonyms : | IGFBP7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; FSTL2; IGFBP 7; MAC25; PSF; IGFBP-rP1; angiomodulin; IGF-binding protein 7; PGI2-stimulating factor; tumor-derived adhesion factor; prostacyclin-stimulating factor; AGM; TAF; IBP-7; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; |
Gene ID : | 3490 |
mRNA Refseq : | NM_001253835 |
Protein Refseq : | NP_001240764 |
MIM : | 602867 |
UniProt ID : | Q16270 |
Products Types
◆ Recombinant Protein | ||
IGFBP7-3141H | Recombinant Human IGFBP7 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP7-529H | Recombinant Human IGFBP7 Protein, MYC/DDK-tagged | +Inquiry |
IGFBP7-303H | Recombinant Human IGFBP7 Protein, His-tagged | +Inquiry |
IGFBP7-1656H | Recombinant Human IGFBP7 Protein, His&GST-tagged | +Inquiry |
IGFBP7-2281H | Recombinant Human IGFBP7 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IGFBP7-1694HCL | Recombinant Human IGFBP7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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