Recombinant Human IL-6 Protein

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Recombinant Human IL-6 Protein

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Cat.No. : IL6R-1058H
Product Overview : Recombinant Human interleukin-6 antigen is produced by E.coli expression system and the target gene encoding Pro29-Met212 is expressed. Predicted molecular weight: 21 kDa.
Source : E.coli
Species : Human
Form : IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is relevant to many disease processes such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic lupus erythematosus, cancer, and rheumatoid arthritis. There is an interest in developing anti-IL-6 agents as therapy against many of these diseases. The first such is tocilizumab which has been approved for rheumatoid arthritis.
Molecular Mass : 21 kDa
Purity : > 90 % by SDS-PAGE
Storage : -20 centigrade
Concentration : 0.5 mg/ml when reconstituted with 100 µl of deionized water
Storage Buffer : 20 mM Hac-NaAc, pH 5.0, 150 mM NaCl
Gene Name : IL6R interleukin 6 receptor [ Homo sapiens ]
Official Symbol : IL6R
Synonyms : IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1; MGC104991;
Gene ID : 3570
mRNA Refseq : NM_000565
Protein Refseq : NP_000556
MIM : 147880
UniProt ID : P08887

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