Recombinant Human IL12B & IL23A Heterotrimer Protein (Met1-Ser328 & Arg20-Pro189), His-tagged, Biotinylated
Cat.No. : | IL23-1037H |
Product Overview : | Recombinant Human IL12B & IL23A Heterotrimer Protein (NP_002178.2)(Met1-Ser328) & (NP_057668.1)(Arg20-Pro189) was produced by HEK293 Cells expression system. This protein was linked by a polypeptide linker was fused with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ile 23 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human IL23 complex (IL23A&IL12B) consists 502 amino acids and predicts a molecular mass of 55.8 kDa. |
Protein length : | Met1-Ser328 & Arg20-Pro189 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Shipping : | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Gene Name : | IL12B interleukin 12B [ Homo sapiens (human) ] & IL23A interleukin 23 subunit alpha [ Homo sapiens (human) ] |
Official Symbol : | IL12B & IL23A |
Synonyms : | CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B & P19; SGRF; IL-23; IL-23A; IL23P19 |
Gene ID : | 3593 & 51561 |
mRNA Refseq : | NM_002187 & NM_016584 |
Protein Refseq : | NP_002178 & NP_057668 |
UniProt ID : | P29460 & Q9NPF7 |
Products Types
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IL23-160M | Recombinant Mouse IL23(Val22-Ala196&Met23-Ser335) Protein, None-tagged | +Inquiry |
Il12b&Il23a-156M | Active Recombinant Mouse Il12b&Il23a, HIgG1 Fc-tagged | +Inquiry |
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◆ Lysates | ||
IL23-1094MCL | Recombinant Mouse IL23 cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIL23 expression correlates with disease severity in psoriasis.
IL23 expression varies among dendritic cells and macrophages.
IL23 activates STAT3 to modulate downstream targets.
IL23 interacts with IL-12 to form a signaling cascade.
IL23 is involved in the activation of STAT3.
IL23 expression is upregulated in autoimmune diseases like Crohn's.
The half-life of IL23 in plasma is approximately 2 hours.
IL23 induces M1 macrophage polarization.
IL23 promotes Th17 cell differentiation by activating STAT3.
IL23 contributes to tissue inflammation by activating macrophages.
Customer Reviews (3)
Write a reviewHigh purity levels in CHIP
Effective in T-cell differentiation.
Suitable for signaling studies.
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