Recombinant Human IL1RAPL1 protein(Met1-Leu354), hFc-tagged

• Cat.No.: IL1RAPL1-776H
• Product Overview: Recombinant Human IL1R8 (NP_055086.1) (Met 1-Leu 354) was expressed in HEK293, fused with the Fc region of Human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 1-354 a.a.
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Bio-activity: Measured by its ability to bind biotinylated human IL1α in functional ELISA.
• Molecular Mass: The recombinant human IL1R8/Fc is a disulfide-linked homodimer. The reduced monomer consists of 574 amino acids and has a predicted molecular mass of 65 kDa. As a result of glycosylation, the rh IL1R8/Fc monomer migrates with an apparent molecular mass of 80-85 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: IL1RAPL1 interleukin 1 receptor accessory protein-like 1 [ Homo sapiens ]
• Official Symbol: IL1RAPL1
• Synonyms: IL1RAPL1; interleukin 1 receptor accessory protein-like 1; IL1RAPL, mental retardation, X linked 10 , mental retardation, X linked 21 , mental retardation, X linked 34 , MRX10, MRX21, MRX34; interleukin-1 receptor accessory protein-like 1; IL1R8; OPHN4; TIGIRR 2; IL1RAPL-1; IL-1RAPL-1; IL-1-RAPL-1; oligophrenin-4; interleukin 1 receptor-8; mental retardation, X-linked 10; X-linked interleukin-1 receptor accessory protein-like 1; three immunoglobulin domain-containing IL-1 receptor-related 2; MRX10; MRX21; MRX34; IL1RAPL; TIGIRR-2
• Gene ID: 11141
• mRNA Refseq: NM_014271
• Protein Refseq: NP_055086
• MIM: 300206
• UniProt ID: Q9NZN1