Recombinant Human IL1RL2 protein, Fc-tagged
|Product Overview :||Recombinant Human IL1RL2 protein (Asp20-Arg335), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293).|
- Gene Information
- Related Products
|Description :||The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.|
|Tag :||human IgG1 Fc|
|Form :||Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose.|
|Molecular Mass :||The protein has a calculated MW of 62.4 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Protein length :||316|
|Endotoxin :||Less than 1.0 EU per ug by the LAL method.|
|Purity :||>95% as determined by SDS-PAGE.|
|Storage :||For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.|
|Gene Name :||IL1RL2|
|Official Symbol :||IL1RL2|
|Synonyms :||IL1RL2; interleukin 1 receptor-like 2; interleukin-1 receptor-like 2; IL1R rp2; IL1RRP2; IL-1Rrp2; interleukin-1 receptor-related protein 2; IL1R-rp2|
|Gene ID :||8808|
|mRNA Refseq :||NM_003854|
|Protein Refseq :||NP_003845|
|UniProt ID :||Q9HB29|
|◆ Recombinant Protein|
|Il1rl2-6384R||Recombinant Rat Il1rl2 Protein, His (Fc)-Avi-tagged||+Inquiry|
|IL1RL2-1983M||Recombinant Mouse IL1RL2 Protein (22-338 aa), His-tagged||+Inquiry|
|IL1RL2-1980M||Recombinant Mouse IL1RL2(Asp22-Arg338(Ala158Val)) Protein, C-Fc-tagged||+Inquiry|
|Il1rl2-8342R||Recombinant Rat Il1rl2||+Inquiry|
|IL1RL2-0218H||Active Recombinant Human IL1RL2 protein, Fc-tagged||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
Il1rl2 is involved in the development of cardiac hypertrophy.
Il1rl2 expression is upregulated in response to bacterial infection.
Il1rl2 induces M2 macrophage polarization.
Il1rl2 has high affinity for its primary ligand, IL-36.
Il1rl2 promotes adipogenesis by activating PPAR-gamma.
The half-life of Il1rl2 in serum is approximately 30 minutes.
Il1rl2 interacts with IL-36R on the cell membrane.
Il1rl2 undergoes phosphorylation.
Il1rl2 increases blood-brain barrier permeability.
Il1rl2 expression is not influenced by circadian rhythms.
Customer Reviews (3)Write a review
High purity. -
Good for receptor binding. -
Effective in inflammation assays. -
Ask a Question for All IL1RL2 Products
Required fields are marked with *
My Review for All IL1RL2 Products
Required fields are marked with *