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Recombinant Human IL1RL2 protein, hFc-tagged

Cat.No. : IL1RL2-319H
Product Overview : Recombinant Human IL1RL2 protein(Q9HB29-1)(Asp20-Arg335), fused with C-terminal hFc tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : C-hFc
Protein length : Asp20-Arg335
Form : Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Bio-activity : Immobilized Human IL-1 Rrp-2, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-1 Rrp-2 Antibody, hFc Tag with the EC50 of 20.9ng/ml determined by ELISA (QC Test).
Molecular Mass : The protein has a predicted MW of 62.6 kDa. Due to glycosylation, the protein migrates to 75-110 kDa based on Tris-Bis PAGE result.
Endotoxin : Less than 1EU per μg by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Storage : Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL1RL2 interleukin 1 receptor-like 2 [ Homo sapiens ]
Official Symbol : IL1RL2
Synonyms : IL1RL2; interleukin 1 receptor-like 2; interleukin-1 receptor-like 2; IL1R rp2; IL1RRP2; IL-1Rrp2; interleukin-1 receptor-related protein 2; IL1R-rp2;
Gene ID : 8808
mRNA Refseq : NM_003854
Protein Refseq : NP_003845
MIM : 604512
UniProt ID : Q9HB29

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
11/17/2022

    High purity.

    03/07/2019

      Good for receptor binding.

      10/14/2018

        Effective in inflammation assays.

        Q&As (10)

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        What is the role of Il1rl2 in cardiac hypertrophy? 05/10/2020

        Il1rl2 is involved in the development of cardiac hypertrophy.

        How does Il1rl2 expression change in response to bacterial infection? 01/01/2019

        Il1rl2 expression is upregulated in response to bacterial infection.

        How does Il1rl2 affect macrophage polarization? 12/21/2018

        Il1rl2 induces M2 macrophage polarization.

        What is the affinity of Il1rl2 for its primary ligand? 09/08/2018

        Il1rl2 has high affinity for its primary ligand, IL-36.

        What is the role of Il1rl2 in adipogenesis? 05/14/2018

        Il1rl2 promotes adipogenesis by activating PPAR-gamma.

        What is the half-life of Il1rl2 in serum? 05/11/2018

        The half-life of Il1rl2 in serum is approximately 30 minutes.

        Does Il1rl2 interact with any membrane receptors? 03/15/2018

        Il1rl2 interacts with IL-36R on the cell membrane.

        Does Il1rl2 undergo post-translational modifications? 12/28/2017

        Il1rl2 undergoes phosphorylation.

        Does Il1rl2 contribute to the blood-brain barrier permeability? 12/06/2016

        Il1rl2 increases blood-brain barrier permeability.

        Is Il1rl2 expression influenced by circadian rhythms? 09/28/2016

        Il1rl2 expression is not influenced by circadian rhythms.

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