Recombinant Human IL1RL2 protein, His-Avi-tagged, Biotinylated

• Cat.No.: IL1RL2-0216H
• Product Overview: Biotinylated Recombinant Human IL1RL2 protein(Q9HB29-1)(Asp20-Arg335), fused with C-terminal His and Avi tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: C-His-Avi
• Protein length: Asp20-Arg335
• Conjugation/Label: Biotin
• Form: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
• Bio-activity: Immobilized Biotinylated Human IL-1 Rrp2, His Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA.
• Molecular Mass: The protein has a predicted MW of 39.1 kDa. Due to glycosylation, the protein migrates to 55-75 kDa based on Tris-Bis PAGE result.
• Endotoxin: Less than 1EU per μg by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
• Storage: Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL1RL2 interleukin 1 receptor-like 2 [ Homo sapiens ]
• Official Symbol: IL1RL2
• Synonyms: IL1RL2; interleukin 1 receptor-like 2; interleukin-1 receptor-like 2; IL1R rp2; IL1RRP2; IL-1Rrp2; interleukin-1 receptor-related protein 2; IL1R-rp2
• Gene ID: 8808
• mRNA Refseq: NM_003854
• Protein Refseq: NP_003845
• MIM: 604512
• UniProt ID: Q9HB29

Reviews

11/17/2022

High purity.

03/07/2019

Good for receptor binding.

10/14/2018

Effective in inflammation assays.

Q&As

What is the role of Il1rl2 in cardiac hypertrophy?

Il1rl2 is involved in the development of cardiac hypertrophy.

How does Il1rl2 expression change in response to bacterial infection?

Il1rl2 expression is upregulated in response to bacterial infection.

How does Il1rl2 affect macrophage polarization?

Il1rl2 induces M2 macrophage polarization.

What is the affinity of Il1rl2 for its primary ligand?

Il1rl2 has high affinity for its primary ligand, IL-36.

What is the role of Il1rl2 in adipogenesis?

Il1rl2 promotes adipogenesis by activating PPAR-gamma.

What is the half-life of Il1rl2 in serum?

The half-life of Il1rl2 in serum is approximately 30 minutes.

Does Il1rl2 interact with any membrane receptors?

Il1rl2 interacts with IL-36R on the cell membrane.

Does Il1rl2 undergo post-translational modifications?

Il1rl2 undergoes phosphorylation.

Does Il1rl2 contribute to the blood-brain barrier permeability?

Il1rl2 increases blood-brain barrier permeability.

Is Il1rl2 expression influenced by circadian rhythms?

Il1rl2 expression is not influenced by circadian rhythms.