Recombinant Human IL2 Protein
| Cat.No. : | IL2-14H |
| Product Overview : | Recombinant Human IL2 Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
| Source : | E. coli |
| Species : | Human |
| Tag : | Tag Free |
| Molecular Mass : | The protein has a calculated MW of 57.6 kDa. |
| AA Sequence : | MGADDVVDSSKSFVMENFSSYHGTK PGYVDSIQKGIQKPKSGTQGNYDDD WKGFYSTDNKYDAAGYSVDNENPLS GKAGGVVKVTYPGLTKVLALKVDNA ETIKKELGLSLTEPLMEQVGTEEFI KRFGDGASRVVLSLPFAEGSSSVEY INNWEQAKALSVELEINFETRGKRG QDAMYEYMAQACAGNRVRRSVGSSL SCINLDWDVIRDKTKTKIESLKEHG PIKNKMSESPNKTVSEEKAKQYLEE FHQTALEHPELSELKTVTGTNPVFA GANYAAWAVNVAQVIDSETADNLEK TTAALSILPGIGSVMGIADGAVHHN TEEIVAQSIALSSLMVAQAIPLVGE LVDIGFAAYNFVESIINLFQVVHNS YNRPAYSPGHKTHAPTSSSTKKTQL QLEHLLLDLQMILNGINNYKNPKLT RMLTFKFYMPKKATELKHLQCLEEE LKPLEEVLNLAQSKNFHLRPRDLIS NINVIVLELKGSETTFMCEYADETA TIVEFLNRWITFCQSIISTLT |
| Endotoxin : | < 1 EU/μg by LAL |
| Purity : | > 40% by SDS-PAGE |
| Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : | Denileukin diftitox (0.4 mg/mL)/Total Protein (1.0 mg/mL) |
| Storage Buffer : | Sterile 50 mM Tris, 300 mM NaCl, 400 mM Argine, pH 8.0 |
| Gene Name : | IL2 interleukin 2 [ Homo sapiens (human) ] |
| Official Symbol : | IL2 |
| Synonyms : | IL2; interleukin 2; IL-2; TCGF; lymphokine; interleukin-2; T cell growth factor; aldesleukin; involved in regulation of T-cell clonal expansion |
| Gene ID : | 3558 |
| mRNA Refseq : | NM_000586 |
| Protein Refseq : | NP_000577 |
| MIM : | 147680 |
| UniProt ID : | P01585 |
Products Types
| ◆ Lysates | ||
| IL2-5234HCL | Recombinant Human IL2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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