Recombinant Human IL2RA Protein

Cat.No. : IL2RA-5198H
Product Overview : Human IL2RA (P01589, Glu 22 - Cys 213) partial recombinant protein expressed in HEK293 cells.
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Description : The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. [provided by RefSeq
Source : HEK293
Species : Human
Form : Lyophilized
Molecular Mass : 44 kDa
Endotoxin : < 0.1 ng/μg (1 EU/μg)
Purity : > 90% by SDS-PAGE and HPLC
Applications : SDS-PAGE
Storage : Store at 4 centigrade. For long term storage store at -20 centigrade or -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : Lyophilized from PBS, pH 7.2
Gene Name : IL2RA interleukin 2 receptor, alpha [ Homo sapiens ]
Official Symbol : IL2RA
Synonyms : IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; TCGFR; IDDM10;
Gene ID : 3559
mRNA Refseq : NM_000417
Protein Refseq : NP_000408
MIM : 147730
UniProt ID : P01589

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there any adverse effect of IL2RA combined with other drugs? 12/10/2022

The combination of IL2RA and other drugs may produce nausea, vomiting, rash and other adverse reactions, should be monitored.

How often is IL2RA used? 01/11/2022

The frequency of use of IL2RA depends on the specific situation of the patient, and is generally used 1-3 times per week.

Whether there is an effect of IL2RA? 12/17/2021

IL2RA, in the right dosage and frequency of use, can significantly relieve symptoms of diseases such as autoimmune diseases and organ transplant rejection.

Can IL2RA treat cancer? 05/18/2021

Can assist in the treatment of some types of malignant tumors, but it is not a complete cure for cancer.

How effective is IL2RA treatment? 04/07/2020

The effective rate of IL2RA therapy depends on many factors such as the type of disease, the patient's condition and the treatment regimen, and the effective rate is generally between 50% and 90%.

What are the indications for IL2RA? 01/09/2020

Indications of IL2RA include a variety of autoimmune diseases, organ transplant rejection and malignant tumors.

Customer Reviews (3)

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Reviews
09/29/2022

    Structural stability of IL2RA, that is, whether it can maintain its structural integrity and functional activity under different conditions such as temperature, pH value and storage time, HPLC, CD spectroscopy and other techniques can be used to evaluate the stability. -

    06/05/2021

      Solubility and stability of IL2RA in physiological buffers to ensure its reliability in practical applications. -

      03/14/2019

        To evaluate whether IL2RA has biological activity, we can verify its IL-2 binding ability and signal transduction ability through cell experiments, which are the key functions of IL2RA. -

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