Recombinant Human IL33 protein, FLAG-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | IL33-29791TH Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human IL33(aa 112-270) fused with FLAG tag at C-terminal was expressed in HEK293. |
Description : | Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis. |
Source : | HEK293 |
Species : | Human |
Tag : | FLAG |
Form : | Liquid. 0.2μm-filtered solution in PBS, pH 7.2. |
Bio-activity : | Activates human ST2-dependent NF-κB pathway. |
Molecular Mass : | ~23kDa (SDS-PAGE) |
Endotoxin : | <0.1EU/μg purified protein (LAL test; Lonza). |
Purity : | ≥90% (SDS-PAGE) |
Stability : | Working aliquots are stable for up to 3 months when stored at -20 centigrade. |
Storage : | Short Term Storage +4 centigrade;Long Term Storage -20 centigrade;After opening, prepare aliquots and store at -20 centigrade. Avoid freeze/thaw cycles. |
Concentration : | 1mg/ml |
Gene Name : | IL33 interleukin 33 [ Homo sapiens ] |
Official Symbol : | IL33 |
Synonyms : | IL33; interleukin 33; C9orf26, chromosome 9 open reading frame 26 (NF HEV); interleukin-33; DKFZp586H0523; DVS27; DVS27 related protein; IL1F11; interleukin 1 family; member 11; NF HEV; nuclear factor for high endothelial venules; IL-33; IL-1F11; DVS27-related protein; interleukin-1 family member 11; nuclear factor from high endothelial venules; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2; |
Gene ID : | 90865 |
mRNA Refseq : | NM_001199640 |
Protein Refseq : | NP_001186569 |
MIM : | 608678 |
UniProt ID : | O95760 |
Chromosome Location : | 9p24.1 |
Pathway : | Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; |
Function : | cytokine activity; protein binding; |
◆ Recombinant Protein
Il33-026I | Recombinant Mouse Il33 Protein (158 aa) | +Inquiry |
IL33-2700R | Recombinant Rat IL33 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL33-095I | Recombinant Human IL33 Protein (159 aa) | +Inquiry |
IL33-2313H | Recombinant Human IL33 Protein, His-tagged | +Inquiry |
IL33-1917M | Recombinant Mouse IL33 Protein | +Inquiry |
|
◆ Lysates
IL33-5226HCL | Recombinant Human IL33 293 Cell Lysate | +Inquiry |
|
IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy