| Species : |
Human |
| Source : |
Insect Cells |
| Tag : |
His |
| Protein Length : |
21-242 a.a. |
| Description : |
IL34, also known as interleukin-34 isoform 1, is a secreted cytokine. This protein is expressed in a variety of tissues richest in the spleen and stimulates the proliferation of monocytes. In a functional study, IL-34, such as CSF-1, another ligand for CSF-1R, stimulated phosphorylation of extracellular signal-regulated kinase-1 and -2 (ERK1 / 2) in human monocytes. In addition, it promoted the formation of macrophage precursor colonization units-macrophages (CFU-M) in human bone marrow cultures. |
| Form : |
Liquid |
| Molecular Mass : |
26.3 kDa |
| N-terminal Sequence Analysis : |
Ala |
| Endotoxin : |
< 1.0 EU per 1 μg of protein (determined by LAL method) |
| Purity : |
> 90% by SDS - PAGE |
| Storage : |
Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : |
0.25 mg/mL (determined by Absorbance at 280nm) |
| Storage Buffer : |
In 20mM Tris-Hcl buffer (pH 8.5) containing 1mM DTT, 0.15M NaCl, 01mM PMSF, 1mM EDTA, 30% glycerol. |
| Warning : |
For research use only. This product is not intended or approved for human, diagnostics or veterin |
| AA Sequence : |
ADPNEPLEMWPLTQNEECTVTGFLRDKLQYRSRLQYMKHYFPINYKISVPYEGVFRIANVTRLQRAQVSERELRYLWVLVSLSATESVQDVLLEGHPSWKYLQEVQTLLLNVQQGLTDVEVSPKVESVLSLLNAPGPNLKLVRPKALLDNCFRVMELLYCSCCKQSSVLNWQDCEVPSPQSCSPEPSLQYAATQLYPPPPWSPSSPPHSTGSVRPVRAQGEGLLPHHHHHH |
