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Recombinant Human IL36G Protein

Cat.No. : IL36G-85H
Product Overview : Recombinant Human Interleukin-36 gamma is produced by our E.coli expression system and the target gene encoding Ser18-Asp169 is expressed.
  • Specification
  • Gene Information
  • Related Products
Description : Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.
Source : E. coli
Species : Human
Form : Lyophilized from a 0.2 um filtered solution of 20mM Tris,100mM Nacl, 0.1mM EDTA, pH8.0.
Protein Length : Ser18-Asp169
AA Sequence : SMCKPITGTINDLNQQVWTLQGQNL VAVPRSDSVTPVTVAVITCKYPEAL EQGRGDPIYLGIQNPEMCL YCEKVGEQPTLQLKEQKIMDLYGQP EPVKPFLFYRAKTGRTSTLESVAFP DWFIASSKRDQPIILTSELG KSYNTAFELNIND
Endotoxin : Less than 0.1 ng/ug (1 EU/ug).
Purity : >95%
Storage : Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
Quality Statement : Purity: Greater than 95% as determined by reducing SDS-PAGE.
Shipping : The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
Gene Name : IL36G interleukin 36 gamma [ Homo sapiens (human) ]
Official Symbol : IL36G
Synonyms : Interleukin-36 gamma; IL36G; IL-1-related protein 2; IL-1 epsilon; Interleukin-1 homolog 1; IL1E; IL1F9; IL1H1; IL-1F9; IL-1H1; IL1RP2; IL-1RP2
Gene ID : 56300
mRNA Refseq : NM_019618.4
Protein Refseq : NP_062564.1
MIM : 605542
UniProt ID : Q9NZH8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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