Species : |
Human |
Source : |
E.coli |
Description : |
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2. This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
Form : |
Affinity purified, liquid |
Molecular Mass : |
15.5 kDa |
Purity : |
>95% pure by SDS-PAGE |
Applications : |
Suitable for use in ELISA, WB and other immune tests |
Storage : |
Upon receipt, store at 2-8 centigrade. |
Storage Buffer : |
Phosphate saline, pH 8, and 8 M Urea |
Full Length : |
Full L. |