Recombinant Human IL5 Protein, His-tagged
Cat.No. : | IL5-76H |
Product Overview : | Recombinant Human Interleukin-5 is produced by our Mammalian expression system and the target gene encoding Ile20-Ser134 is expressed with a 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Molecular Mass : | Predicted Molecular Weight: 14.2kDa Apparent Molecular Weight: 20kDa, reducing conditions. |
AA Sequence : | Ile20-Ser134 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Purity : | >90% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Purity: Greater than 90% as determined by reducing SDS-PAGE. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | IL5 interleukin 5 [ Homo sapiens (human) ] |
Official Symbol : | IL5 |
Synonyms : | Interleukin-5; IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; IL5; EDF; TRF; IL-5 |
Gene ID : | 3567 |
mRNA Refseq : | NM_000879.3 |
Protein Refseq : | NP_000870.1 |
MIM : | 147850 |
UniProt ID : | P05113 |
Products Types
◆ Recombinant Protein | ||
IL5-2177C | Active Recombinant Canine IL5 Protein, His-tagged | +Inquiry |
Il5-1043M | Recombinant Mouse Il5 Protein, His-tagged | +Inquiry |
Il5-207M | Recombinant Active Mouse IL5 Protein, His-tagged(C-ter) | +Inquiry |
IL5-0018H | Recombinant Human IL5 Protein | +Inquiry |
IL5-312H | Active Recombinant Human IL5 protein(Ile20-Ser134) | +Inquiry |
◆ Lysates | ||
IL5-496MCL | Recombinant Mouse IL5 cell lysate | +Inquiry |
IL5-456CCL | Recombinant Canine IL5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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