Recombinant Human IL6 Protein

• Cat.No.: IL6-61H
• Product Overview: Recombinant Human Interleukin-6 is produced by our E.coli expression system and the target gene encoding Val30-Met212 is expressed.

Specification

• Species: Human
• Source: E.coli
• Protein Length: -6 a.a.
• Description: Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues. IL-6 is secreted by several cell types including T cells and macrophages. IL-6 plays a critical role in the immune response and acute phase reactions. IL-6 is also important in hematopoiesis, bone metabolism, and cancer progression, and has been identified as an essential role in directing the transition from innate to acquired immunity. IL-6 has been also shown to inhibit the growth of early stage and to promote the proliferation of advanced-stage melanoma cells in vitro.
• Form: Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
• Molecular Mass: Predicted Molecular Weight: 21.1kDa
  Apparent Molecular Weight: 18.4-25kDa, reducing conditions.
• AA Sequence: Val30-Met212
• Endotoxin: Less than 1 EU/ug.
• Purity: >90%
• Storage: Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
  Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
• Reconstitution: It is not recommended to reconstitute to a concentration less than 100μg/ml.
  Dissolve the lyophilized protein in distilled water.
  Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Quality Statement: Purity: greater than 90% as determined by reducing SDS-PAGE.
• Shipping: The product is shipped at ambient temperature.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: IL6 interleukin 6 [ Homo sapiens (human) ]
• Official Symbol: IL6
• Synonyms: Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2
• Gene ID: 3569
• mRNA Refseq: NM_000600.5
• Protein Refseq: NP_000591.1
• MIM: 147620
• UniProt ID: P05231