Recombinant Human IL6 Protein
Cat.No. : | IL6-61H |
Product Overview : | Recombinant Human Interleukin-6 is produced by our E.coli expression system and the target gene encoding Val30-Met212 is expressed. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues. IL-6 is secreted by several cell types including T cells and macrophages. IL-6 plays a critical role in the immune response and acute phase reactions. IL-6 is also important in hematopoiesis, bone metabolism, and cancer progression, and has been identified as an essential role in directing the transition from innate to acquired immunity. IL-6 has been also shown to inhibit the growth of early stage and to promote the proliferation of advanced-stage melanoma cells in vitro. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. |
Molecular Mass : | Predicted Molecular Weight: 21.1kDa Apparent Molecular Weight: 18.4-25kDa, reducing conditions. |
AA Sequence : | Val30-Met212 |
Endotoxin : | Less than 1 EU/ug. |
Purity : | >90% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. |
Reconstitution : | It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Purity: greater than 90% as determined by reducing SDS-PAGE. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | IL6 interleukin 6 [ Homo sapiens (human) ] |
Official Symbol : | IL6 |
Synonyms : | Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2 |
Gene ID : | 3569 |
mRNA Refseq : | NM_000600.5 |
Protein Refseq : | NP_000591.1 |
MIM : | 147620 |
UniProt ID : | P05231 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.
The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.
Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.
Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.
This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.
The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.
Customer Reviews (3)
Write a reviewAccurate localization and function within the cell.
The binding affinity and affinity constant with the target are high.
Can form a stable micellar structure.
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