Recombinant Human IL6R protein, His-Avi-tagged

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Recombinant Human IL6R protein, His-Avi-tagged

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Cat.No. : IL6R-087H
Product Overview : Human IL-6R alpha Protein is expressed from mammalian with a His and Avi tag at the C-terminal. It contains Leu 20 - Pro 365.
Description : The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha ) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The protein has a predicted MW of 41.4 kDa.Due to glycosylation, the protein migrates to 65- 78KDa based on Bis-Tris PAGE result.
Protein length : It contains Leu 20 - Pro 365.
Endotoxin : Less than 0.01EU per ug by the LAL method
Purity : > 95% as determined by SDS-PAGE; > 94% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

HPLC data :

Gene Name : IL6R interleukin 6 receptor [ Homo sapiens ]
Official Symbol : IL6R
Synonyms : CD126; gp80; IL-6 R alpha; IL6Q; IL6R alpha; IL-6R alpha; IL6R; IL-6R-1; IL6RA; IL-6Ra; IL6RQ; interleukin 6 receptor1
Gene ID : 3570
mRNA Refseq : NM_000565
Protein Refseq : NP_000556
MIM : 147880
UniProt ID : P08887

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