Recombinant Human IL6R protein, His-Avi-tagged IL6R-087H

Recombinant Human IL6R protein, His-Avi-tagged

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Cat.No. :	IL6R-087H
Product Overview :	Human IL-6R alpha Protein is expressed from mammalian with a His and Avi tag at the C-terminal. It contains Leu 20 - Pro 365.
Description :	The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha ) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.
Source :	HEK293
Species :	Human
Tag :	His-Avi
Form :	Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass :	The protein has a predicted MW of 41.4 kDa.Due to glycosylation, the protein migrates to 65- 78KDa based on Bis-Tris PAGE result.
Protein length :	It contains Leu 20 - Pro 365.
Endotoxin :	Less than 0.01EU per ug by the LAL method
Purity :	> 95% as determined by SDS-PAGE; > 94% as determined by HPLC
Storage :	The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution :	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :
HPLC data :

Gene Name :	IL6R interleukin 6 receptor [ Homo sapiens ]
Official Symbol :	IL6R
Synonyms :	CD126; gp80; IL-6 R alpha; IL6Q; IL6R alpha; IL-6R alpha; IL6R; IL-6R-1; IL6RA; IL-6Ra; IL6RQ; interleukin 6 receptor1
Gene ID :	3570
mRNA Refseq :	NM_000565
Protein Refseq :	NP_000556
MIM :	147880
UniProt ID :	P08887