Recombinant Human IL7RA protein, Fc-tagged

Cat.No. : IL7RA-328H
Product Overview : Recombinant Human IL7RA protein (Glu21-Gly236), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293).
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  • Gene Information
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Description : Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra/CD127 contains 1 fibronectin type-III domain. IL7Ra/CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra/CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
Source : HEK293
Species : Human
Tag : human IgG1 Fc
Form : Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 51.0 kDa. The protein migrates as 66-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : 216
Endotoxin : Less than 1.0 EU per ug by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : IL7RA
Official Symbol : IL7RA
Synonyms : ILRA; CD127; IL7RA; CDW127; IL-7R-alpha
Gene ID : 3575
mRNA Refseq : NM_002185.5
Protein Refseq : NP_002176.2
MIM : 146661
UniProt ID : P16871

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (6)

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Can AIDS be prevented by IL7RA? 12/08/2022

It is not used to prevent AIDS methods, currently mainly used for disease treatment.

Is IL7RA associated with immunity enhancement? 02/10/2022

Yes, the IL7RA can enhance the function of immune cells and thus enhance immunity.

Does the use of IL7RA require special storage conditions? 12/28/2021

Yes, the IL7RA needs to be stored under low temperature and dry conditions to maintain its stability.

Is recombinant IL7RA associated with cancer? 10/24/2020

IL7RA has also been studied in cancer immunotherapy, but the specific effect needs to be further verified.

What are the side effects of IL7RA? 12/08/2019

The side effects of IL7RA include fever, headache, fatigue, etc. In rare cases, allergic reactions may occur.

What is the action mechanism of IL7RA? 05/19/2019

This protein activates T cells and B cells by binding to IL-7 receptors, promoting the enhancement of immune response.

Customer Reviews (3)

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    This synthesis cost and application cost are moderate, and it is more cost-effective for production. -


      IL7RA has good stability and consistency in the process of mass production. -


        Long-lasting effects and sustained release properties. -

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