Recombinant Human IL9R Protein, C-His-tagged

• Cat.No.: IL9R-072H
• Product Overview: Recombinant Human IL9R Protein with C-His tag was expressed in E. coli.

Specification

• Description: Interleukin-9 (IL-9) functions to support the growth of helper T cells, megakaryoblastic leukemia cells, fetal thymocytes, erythroid and myeloid precursors and mast cells. The murine IL-9 receptor has been identified as a protein expressed on a T cell clone. Both the murine and human IL-9 receptor cDNAs have been isolated by expression cloning from the murine T cell clone TS1 and the human megakaryoblastic leukemia cell line MO7E, respectively. In addition, the cloning and analysis of the complete human IL-9 receptor genomic DNA has been reported. In this latter study, the IL-9R gene was shown to consist of 10 exons expressed over approximately 13.7 kb of DNA.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: ~25 kDa
• AA Sequence: SVTGEGQGPRSRTFTCLTNNILRID CHWSAPELGQGSSPWLLFTSNQAPG GTHKCILRGSECTVVLPPEAVLVPS DNFTITFHHCMSGREQVSLVDPEYL PRRHVKLDPPSDLQSNISSGHCILT WSISPALEPMTTLLSYELAFKKQEE AWEQAQHRDHIVGVTWLILEAFELD PGFIHEARLRVQMATLEDDVVEEER YTGQWSEWSQPVCFQAPQRQGPLIP PWGWP
• Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
• Concentration: ≥0.5 mg/mL
• Storage Buffer: PBS, 4M Urea, pH7.4

Gene Information

• Gene Name: IL9R interleukin 9 receptor [ Homo sapiens (human) ]
• Official Symbol: IL9R
• Synonyms: IL9R; interleukin 9 receptor; interleukin-9 receptor; CD129; IL-9R; IL-9 receptor
• Gene ID: 3581
• mRNA Refseq: NM_002186
• Protein Refseq: NP_002177
• MIM: 300007
• UniProt ID: Q01113

Reviews

05/10/2022

IL9R is very advanced and adopts the most environmentally friendly production process, which is worth vigorously promoting.

01/11/2022

The reproducibility of IL9R is very good, and the results are very consistent in each experiment or application, thanks to its high stability and reproducibility, which provides great convenience for follow-up studies.

02/27/2020

IL9R produced by them are widely used and suitable for various biological experiments.

Q&As

Can the treatment of cancer with IL9R improve the immune system of patients?

In pre-clinical trials, the IL9R significantly increased natural killer and CD4 + T cell levels in patients.

What somatic cell therapy-based data updates can recombinant IL9R be used for?

IL9R may play an important role in the treatment of central nervous system diseases and hematological diseases.

In which tumor therapies are recombinant IL9R most likely to be effective?

This needs to be further confirmed by large-scale clinical trials.

What techniques are used to study the relationship between IL9R and cancer?

This can be achieved through in vitro molecular cell techniques and carefully designed in vivo animal models.

Which diseases might be treated by recombinant IL9R?

There have been no large-scale clinical studies to prove which diseases the recombinant IL9R protein can treat.

Is the expression of IL9R in tumor cells correlated with patient prognosis?

Some studies have suggested that the expression of IL9R in tumor cells may be associated with patient prognosis.