Recombinant Human Interleukin 1 Receptor-Like 2
| Cat.No. : | IL1RL2-1639H |
- Specification
- Gene Information
- Related Products
| Cat. No. : | IL1RL2-1639H |
| Description : | Interleukin-1 receptor related protein 2 (IL-1 Rrp2) is a receptor for IL-1F6 which is a proinflammatory member of IL-1 family. IL-1F8, and IL-1F9 also signal through IL-1Rrp2 and IL-1RAcP. IL-1F6, IL-1F8 and Il-1F9 are agonists and, along with their receptor IL-1Rrp2, are highly expressed in epithelial cells suggesting a role in immune defense in the skin and the gastrointestinal (GI) tract including the mouth. Synovial fibroblasts and articular chondrocytes also express IL-1Rrp2 and respond to IL-1F8, indicating a possible role in rheumatoid arthritis (RA). |
| Source : | Sf 21 Insect Cells. |
| State Of Matter : | Lyophilized. |
| Purity : | >95% by SDS Page and analyzed by silver stain. |
| Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
| Molecular Weight : | The predicted molecular weight of Recombinant Human IL-1 Rrp2 is Mr 62.8 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 80 kDa. |
| Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Gene Name : | IL1RL2 interleukin 1 receptor-like 2 [ Homo sapiens ] |
| Synonyms : | interleukin 1 receptor-like 2; IL1RRP2; IL1R-rp2; IL1RL2; interleukin-1 receptor-related protein 2; IL-1Rrp2; IL1R-rp2; IL1RRP2 |
| Gene ID : | 8808 |
| mRNA Refseq : | NM_003854 |
| Protein Refseq : | NP_003845 |
| MIM : | 604512 |
| UniProt ID : | Q9HB29 |
| Chromosome Location : | 2q12 |
| Function : | interleukin-1, Type I, activating receptor activity; transmembrane receptor activity |
Products Types
| ◆ Recombinant Protein | ||
| Il1rl2-6384R | Recombinant Rat Il1rl2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| IL1RL2-1983M | Recombinant Mouse IL1RL2 Protein (22-338 aa), His-tagged | +Inquiry |
| IL1RL2-0216H | Active Recombinant Human IL1RL2 protein, His-Avi-tagged, Biotinylated | +Inquiry |
| IL1RL2-1980M | Recombinant Mouse IL1RL2(Asp22-Arg338(Ala158Val)) Protein, C-Fc-tagged | +Inquiry |
| IL1RL2-319H | Active Recombinant Human IL1RL2 protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIl1rl2 is involved in the development of cardiac hypertrophy.
Il1rl2 expression is upregulated in response to bacterial infection.
Il1rl2 induces M2 macrophage polarization.
Il1rl2 has high affinity for its primary ligand, IL-36.
Il1rl2 promotes adipogenesis by activating PPAR-gamma.
The half-life of Il1rl2 in serum is approximately 30 minutes.
Il1rl2 interacts with IL-36R on the cell membrane.
Il1rl2 undergoes phosphorylation.
Il1rl2 increases blood-brain barrier permeability.
Il1rl2 expression is not influenced by circadian rhythms.
Customer Reviews (3)
Write a reviewHigh purity. -
Good for receptor binding. -
Effective in inflammation assays. -
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