Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Interleukin 1 Receptor-Like 2

Cat.No. : IL1RL2-1639H
  • Specification
  • Gene Information
  • Related Products
Cat. No. : IL1RL2-1639H
Description : Interleukin-1 receptor related protein 2 (IL-1 Rrp2) is a receptor for IL-1F6 which is a proinflammatory member of IL-1 family. IL-1F8, and IL-1F9 also signal through IL-1Rrp2 and IL-1RAcP. IL-1F6, IL-1F8 and Il-1F9 are agonists and, along with their receptor IL-1Rrp2, are highly expressed in epithelial cells suggesting a role in immune defense in the skin and the gastrointestinal (GI) tract including the mouth. Synovial fibroblasts and articular chondrocytes also express IL-1Rrp2 and respond to IL-1F8, indicating a possible role in rheumatoid arthritis (RA).
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-1 Rrp2 is Mr 62.8 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 80 kDa.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name : IL1RL2 interleukin 1 receptor-like 2 [ Homo sapiens ]
Synonyms :
interleukin 1 receptor-like 2; IL1RRP2; IL1R-rp2; IL1RL2; interleukin-1 receptor-related protein 2; IL-1Rrp2; IL1R-rp2; IL1RRP2
Gene ID : 8808
mRNA Refseq : NM_003854
Protein Refseq : NP_003845
MIM : 604512
UniProt ID : Q9HB29
Chromosome Location : 2q12
Function : interleukin-1, Type I, activating receptor activity; transmembrane receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (10)

Ask a question
What is the role of Il1rl2 in cardiac hypertrophy? 05/10/2020

Il1rl2 is involved in the development of cardiac hypertrophy.

How does Il1rl2 expression change in response to bacterial infection? 01/01/2019

Il1rl2 expression is upregulated in response to bacterial infection.

How does Il1rl2 affect macrophage polarization? 12/21/2018

Il1rl2 induces M2 macrophage polarization.

What is the affinity of Il1rl2 for its primary ligand? 09/08/2018

Il1rl2 has high affinity for its primary ligand, IL-36.

What is the role of Il1rl2 in adipogenesis? 05/14/2018

Il1rl2 promotes adipogenesis by activating PPAR-gamma.

What is the half-life of Il1rl2 in serum? 05/11/2018

The half-life of Il1rl2 in serum is approximately 30 minutes.

Does Il1rl2 interact with any membrane receptors? 03/15/2018

Il1rl2 interacts with IL-36R on the cell membrane.

Does Il1rl2 undergo post-translational modifications? 12/28/2017

Il1rl2 undergoes phosphorylation.

Does Il1rl2 contribute to the blood-brain barrier permeability? 12/06/2016

Il1rl2 increases blood-brain barrier permeability.

Is Il1rl2 expression influenced by circadian rhythms? 09/28/2016

Il1rl2 expression is not influenced by circadian rhythms.

Customer Reviews (3)

Write a review
Reviews
11/17/2022

    High purity.

    03/07/2019

      Good for receptor binding.

      10/14/2018

        Effective in inflammation assays.

        Ask a Question for All IL1RL2 Products

        Required fields are marked with *

        My Review for All IL1RL2 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends