| Cat.No. : |
IL1RL2-1639H
Optional Service: Optional requirements on this protein
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| Description : |
Interleukin-1 receptor related protein 2 (IL-1 Rrp2) is a receptor for IL-1F6 which is a proinflammatory member of IL-1 family. IL-1F8, and IL-1F9 also signal through IL-1Rrp2 and IL-1RAcP. IL-1F6, IL-1F8 and Il-1F9 are agonists and, along with their receptor IL-1Rrp2, are highly expressed in epithelial cells suggesting a role in immune defense in the skin and the gastrointestinal (GI) tract including the mouth. Synovial fibroblasts and articular chondrocytes also express IL-1Rrp2 and respond to IL-1F8, indicating a possible role in rheumatoid arthritis (RA). |
| Source : |
Sf 21 Insect Cells. |
| State Of Matter : |
Lyophilized. |
| Purity : |
>95% by SDS Page and analyzed by silver stain. |
| Endotoxin : |
<1.0 EU/µg as determined by the LAL method. |
| Molecular Weight : |
The predicted molecular weight of Recombinant Human IL-1 Rrp2 is Mr 62.8 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 80 kDa. |
| Storage And Stability : |
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
