Recombinant Human Interleukin 12B
Cat.No. : | IL12B-177H |
Product Overview : | Recombinant human IL-12 p40 is a 40 kDa protein containing 306 amino acid residues. It was expressed in E.Coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL12B -177H |
Description : | Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23. |
Source : | E.Coli. |
Purity : | > 95% by SDS-PAGE and HPLC analysis. |
Endotoxin Level : | < 0.1 ng per μg of IL-12p40. |
Stabilizer : | None. |
Formulation : | Lyophilized. |
Biological Activity : | Not available. |
Reconstitution : | The human IL-12p40 should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C. |
Stability : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted human IL-12p40 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles. |
Gene Name : | IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) [ Homo sapiens ] |
Synonyms : | OTTHUMP00000160820; CLMF; CLMF2; IL-12B; NKSF; NKSF2; CLMF p40; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL-12 subunit p40; IL12, subunit p40; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 2, p40; interleukin 12, p40; interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); IL12B |
Gene ID : | 3593 |
mRNA Refseq : | NM_002187 |
Protein Refseq : | NP_002178 |
MIM : | 161561 |
UniProt ID : | P29460 |
Chromosome Location : | 5q31.1-q33.1 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Toll-like receptor signaling pathway; Type I diabetes mellitus |
Function : | contributes_to cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-12 alpha subunit binding; interleukin-12 receptor binding; protein binding; protein heterodimerization activity; protein homodimerization activity; signal transducer activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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