Recombinant Human Interleukin 2 Receptor, Alpha, GST-tagged
|Product Overview :||Recombinant Human IL-2R full length protein expressed inE.colishows a 53 kDa band on SDS-PAGE (Including GST tag). The IL-2R is purified by proprietary chromatographic techniques.|
- Gene Information
- Related Products
|Cat. No. :||IL2RA-1325H|
|Description :||IL-2R (T-cell growth factor receptor) consists of a chain of 55 kDa (also known as Tac antigen or p55 or alpha chain) and a p75 or Beta chain. IL-2Ralpha is over-expressed on the surface of activated T-cells, HTLV-1 or -2 positive T-cell lines, and moderately expressed on activated B-cells, NK-cells, and macrophages.|
|Source :||Escherichia Coli.|
|Physical Appearance :||Sterile Filtered clear solution.|
|Formulation :||sIL-2R at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.|
|Applications :||ELISA, Inhibition Assays, Western Blotting.|
|Stability :||Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.|
|Gene Name :||IL2RA interleukin 2 receptor, alpha [ Homo sapiens ]|
|Synonyms :||L2RA; interleukin 2 receptor, alpha; CD25; IL2R; TCGFR; IDDM10; interleukin 2 receptor, alpha chain; Interleukin-2 receptor; IL-2-RA; IL2-RA; OTTHUMP00000019030;OTTHUMP00000044870; p55; CD25 antigen; IL-2 receptor alpha subunit; TAC antigen|
|Gene ID :||3559|
|mRNA Refseq :||NM_000417|
|Protein Refseq :||NP_000408|
|UniProt ID :||P01589|
|Chromosome Location :||10p15-p14|
|Pathway :||Cytokine-cytokine receptor interaction; Endocytosis; Hematopoietic cell lineage; Jak-STAT signaling pathway|
|Function :||interleukin-2 receptor activity; receptor activity|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
The combination of IL2RA and other drugs may produce nausea, vomiting, rash and other adverse reactions, should be monitored.
The frequency of use of IL2RA depends on the specific situation of the patient, and is generally used 1-3 times per week.
IL2RA, in the right dosage and frequency of use, can significantly relieve symptoms of diseases such as autoimmune diseases and organ transplant rejection.
Can assist in the treatment of some types of malignant tumors, but it is not a complete cure for cancer.
The effective rate of IL2RA therapy depends on many factors such as the type of disease, the patient's condition and the treatment regimen, and the effective rate is generally between 50% and 90%.
Indications of IL2RA include a variety of autoimmune diseases, organ transplant rejection and malignant tumors.
Customer Reviews (3)Write a review
Structural stability of IL2RA, that is, whether it can maintain its structural integrity and functional activity under different conditions such as temperature, pH value and storage time, HPLC, CD spectroscopy and other techniques can be used to evaluate the stability. -
Solubility and stability of IL2RA in physiological buffers to ensure its reliability in practical applications. -
To evaluate whether IL2RA has biological activity, we can verify its IL-2 binding ability and signal transduction ability through cell experiments, which are the key functions of IL2RA. -
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