Recombinant Human Interleukin 2 Receptor, Alpha, GST-tagged

Cat.No. : IL2RA-1325H
Product Overview : Recombinant Human IL-2R full length protein expressed inE.colishows a 53 kDa band on SDS-PAGE (Including GST tag). The IL-2R is purified by proprietary chromatographic techniques.
  • Specification
  • Gene Information
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Cat. No. : IL2RA-1325H
Description : IL-2R (T-cell growth factor receptor) consists of a chain of 55 kDa (also known as Tac antigen or p55 or alpha chain) and a p75 or Beta chain. IL-2Ralpha is over-expressed on the surface of activated T-cells, HTLV-1 or -2 positive T-cell lines, and moderately expressed on activated B-cells, NK-cells, and macrophages.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered clear solution.
Formulation : sIL-2R at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Applications : ELISA, Inhibition Assays, Western Blotting.
Stability : Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.
Gene Name : IL2RA interleukin 2 receptor, alpha [ Homo sapiens ]
Synonyms : L2RA; interleukin 2 receptor, alpha; CD25; IL2R; TCGFR; IDDM10; interleukin 2 receptor, alpha chain; Interleukin-2 receptor; IL-2-RA; IL2-RA; OTTHUMP00000019030;OTTHUMP00000044870; p55; CD25 antigen; IL-2 receptor alpha subunit; TAC antigen
Gene ID : 3559
mRNA Refseq : NM_000417
Protein Refseq : NP_000408
MIM : 147730
UniProt ID : P01589
Chromosome Location : 10p15-p14
Pathway : Cytokine-cytokine receptor interaction; Endocytosis; Hematopoietic cell lineage; Jak-STAT signaling pathway
Function : interleukin-2 receptor activity; receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (6)

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Is there any adverse effect of IL2RA combined with other drugs? 12/10/2022

The combination of IL2RA and other drugs may produce nausea, vomiting, rash and other adverse reactions, should be monitored.

How often is IL2RA used? 01/11/2022

The frequency of use of IL2RA depends on the specific situation of the patient, and is generally used 1-3 times per week.

Whether there is an effect of IL2RA? 12/17/2021

IL2RA, in the right dosage and frequency of use, can significantly relieve symptoms of diseases such as autoimmune diseases and organ transplant rejection.

Can IL2RA treat cancer? 05/18/2021

Can assist in the treatment of some types of malignant tumors, but it is not a complete cure for cancer.

How effective is IL2RA treatment? 04/07/2020

The effective rate of IL2RA therapy depends on many factors such as the type of disease, the patient's condition and the treatment regimen, and the effective rate is generally between 50% and 90%.

What are the indications for IL2RA? 01/09/2020

Indications of IL2RA include a variety of autoimmune diseases, organ transplant rejection and malignant tumors.

Customer Reviews (3)

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    Structural stability of IL2RA, that is, whether it can maintain its structural integrity and functional activity under different conditions such as temperature, pH value and storage time, HPLC, CD spectroscopy and other techniques can be used to evaluate the stability. -


      Solubility and stability of IL2RA in physiological buffers to ensure its reliability in practical applications. -


        To evaluate whether IL2RA has biological activity, we can verify its IL-2 binding ability and signal transduction ability through cell experiments, which are the key functions of IL2RA. -

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