Recombinant Human Interleukin 4, HQ-tagged
Cat.No. : | IL4-5334H |
Product Overview : | Recombinant human IL4contains 130 amino acids and a 16 amino acid Histidine/Glutamine-based tagfor a total length of 146 amino acids. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL4-5334H |
Description : | IL-4, is a cytokine that induces differentiationof naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4,Th2 cells subsequently produce additional IL-4. The cell that initiallyproduces IL-4, thus inducing Th0 differentiation, has not been identified,but recent studies suggest that basophils may be the effector cell. |
Source : | Hordeum vulgare(barley grain) |
Species : | Human |
Form : | Lyophilized from a0.2 um sterile filtered solution in 30 mM Sodium Acetate +0.7 M NaCl pH5.3. |
Molecular Weight : | 17.2 kDa |
Purity : | >95% by SDS-PAGE |
Endotoxin Level : | <0.005 ng/ug ofIL4 |
Biological Activity : | Determined by thecell proliferation assay for IL4 for dose- dependent cell proliferation ofhuman TF-1 cells. The EDSO range is 0.8-1.2 ng/mL. |
Specific Activity : | 1.2-0.8 x 106U/mg |
Reconstitution : | Centrifuge vialpriorto opening. Add sterile low salt buffer to the vial to fully solubilizethe protein to a concentration not less than 100 ug/ml. |
Storage : | Although stable atroom temperature for several weeks, lyophilized protein is best stored at-20°C. Store reconstituted protein in working aliquots at -20°C with acarrier protein (0.1% HSA or BSA) as a stabilizer for long term storage.Please note that the addition of any carrier protein into this product mayproduce unwanted endotoxin. This depends upon the particular applicationemployed. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | IL4 |
Gene Name : | IL4 interleukin 4 [ Homosapiens ] |
Synonyms : | IL4; interleukin 4;BSF1; IL-4; BCGF1; BSF-1; BCGF-1; MGC79402; interleukin-4; binetrakin;pitrakinra; OTTHUMP00000066049; OTTHUMP00000066050; B cell growth factor 1;B_cell stimulatory factor 1; lymphocyte stimulatory factor 1 |
Gene ID : | 3565 |
mRNA Refseq : | NM_000589 |
Protein Refseq : | NP_000580 |
MIM : | 147780 |
UniProt ID : | P05112 |
Chromosome Location : | 5q23-q31 |
Pathway : | Allograft rejection;Asthma; Autoimmune thyroid disease; CD40/CD40L signaling; Cytokine-cytokinereceptor interaction; Fc epsilon RI signaling pathway; Hematopoietic celllineage; IL-4 signaling Pathway; IL12-mediated signaling events; IL4-mediatedsignaling events; Inflammatory Response Pathway; Jak-STAT signaling pathway;Leishmaniasis; Measles; T cell receptor signaling pathway |
Function : | cytokine activity;growth factor activity; interleukin-4 receptor binding; protein binding |
Products Types
◆ Recombinant Protein | ||
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IL4-067H | Active Recombinant Human IL4 Protein | +Inquiry |
IL4-178H | Active Recombinant Human IL4 Protein | +Inquiry |
IL4-203H | Recombinant Active Human IL4 Protein, His-tagged(C-ter) | +Inquiry |
IL4-06H | Active Recombinant Human CSF2 and IL4 Fusion Protein, Animal Free | +Inquiry |
◆ Lysates | ||
IL4-001MCL | Recombinant Mouse IL4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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