Recombinant Human IQCB1 Protein, GST-tagged IQCB1-5071H

Recombinant Human IQCB1 Protein, GST-tagged

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Recombinant Human IQCB1 Protein, GST-tagged

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Cat.No. : IQCB1-5071H
Product Overview : Human IQCB1 full-length ORF ( NP_001018865.1, 1 a.a. - 465 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 80.2 kDa
AA Sequence : MKPTGTDPRILSIAA EVAKSPEQNVPVILL KLKEIINITPLGSSE LKKIKQDIYCYDLIQ YCLLVLSQDYSRIQG GWTTISQLTQILSHC CVGLEPGEDAEEFYN ELLPSAAENFLVLGR QLQTCFINAAKAEEK DELLHFFQIVTDSLF WLLGGHVELIQNVLQ SDHFLHLLQADNVQI GSAVMMMLQNILQIN RSKRSKMLLEINRQK EEEDLKLQLQLQRQR AMRLSRELQLSMLEI VHPGQVEKHYREMEE KSALIIQKHWRGYRE RKNFHQQRQSLIEYK AAVTLQRAALKFLAK YRKKKKLFAPWRGLQ ELTDARRVELKKRVD DYVRRHLGSPMSDVV SRELHAQAQERLQHY FMGRALEERAQQHRE ALIAQISTNVEQLMK APSLKEAEGKEPELF LSRSRPVAAKAKQAH LTTLKHIQAPWWKKL GEESGDEIDVPKDEL SIELENLFIGGTKPP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : IQCB1 IQ motif containing B1 [ Homo sapiens ]
Official Symbol : IQCB1
Synonyms : IQCB1; IQ motif containing B1; IQ calmodulin binding motif containing 1; IQ calmodulin-binding motif-containing protein 1; KIAA0036; nephrocystin 5; NPHP5; IQ calmodulin-binding motif containing 1; p53 and DNA damage-regulated IQ motif protein; PIQ; SLSN5;
Gene ID : 9657
mRNA Refseq : NM_001023570
Protein Refseq : NP_001018864
MIM : 609237
UniProt ID : Q15051

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