Recombinant Human IRF3 protein, His-tagged

• Cat.No.: IRF3-60H
• Product Overview: Recombinant Human IRF3, fused with N-His tag, was expressed in E. coli.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
• Molecular Mass: 49.1kDa(including fusion tag)
• Protein length: 442aa(including fusion tag)
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80°C and avoid repeated freeze-thaw cycles

Gene Information

• Gene Name: IRF3 interferon regulatory factor 3 [ Homo sapiens ]
• Official Symbol: IRF3
• Synonyms: IRF3; interferon regulatory factor 3
• Gene ID: 3661
• mRNA Refseq: NM_001197128
• Protein Refseq: NP_001184057
• MIM: 603734
• UniProt ID: Q14653
• Chromosome Location: Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem
• Pathway: DNA binding; identical protein binding; protein binding; protein homodimerization activity; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; transcription cofactor activity