| Description : |
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
53.1 kDa |
| AA Sequence : |
MALHPRRVRLKPWLVAQVDSGLYPG LIWLHRDSKRFQIPWKHATRHSPQQ EEENTIFKAWAVETGKYQEGVDDPD PAKWKAQLRCALNKSREFNLMYDGT KEVPMNPVKIYQVCDIPQPQGSIIN PGSTGSAPWDEKDNDVDEEDEEDEL DQSQHHVPIQDTFPFLNINGSPMAP ASVGNCSVGNCSPEAVWPKTEPLEM EVPQAPIQPFYSSPELWISSLPMTD LDIKFQYRGKEYGQTMTVSNPQGCR LFYGDLGPMPDQEELFGPVSLEQVK FPGPEHITNEKQKLFTSKLLDVMDR GLILEVSGHAIYAIRLCQCKVYWSG PCAPSLVAPNLIERQKKVKLFCLET FLSDLIAHQKGQIEKQPPFEIYLCF GEEWPDGKPLERKLILVQVIPVVAR MIYEMFSGDFTRSFDSGSVRLQIST PDIKDNIVAQLKQLYRILQTQESWQ PMQPTPSMQLPPALPPQTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
