Human IRF6 Knockdown Cell Lysate

• Cat.No.: IRF6-212HKCL
• Product Overview: WB-validated IRF6 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 53 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg IRF6 KD HeLa cell lysate
• Protein Families: ES Cell Differentiation/IPS, Transcription Factors
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: IRF6 interferon regulatory factor 6 [ Homo sapiens (human) ]
• Official Symbol: IRF6
• Synonyms: IRF6; interferon regulatory factor 6; LPS, Van der Woude syndrome, VWS; OFC6; VWS1; LPS; PIT; PPS; VWS
• Gene ID: 3664
• mRNA Refseq: NM_001206696
• Protein Refseq: NP_001193625
• MIM: 607199
• UniProt ID: O14896