Recombinant Human IRS1
Cat.No. : | IRS1-28726TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 600-1245 of Human IRS1 was expressed by baculovirus in Sf9 insect cells using an N-terminal tag, 118kDa. |
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Species : | Human |
Tag : | Non |
Protein Length : | 600-1245 a.a. |
Description : | This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Contains 1 IRS-type PTB domain.Contains 1 PH domain. |
Gene Name | IRS1 insulin receptor substrate 1 [ Homo sapiens ] |
Official Symbol | IRS1 |
Synonyms | IRS1; insulin receptor substrate 1; HIRS 1; |
Gene ID | 3667 |
mRNA Refseq | NM_005544 |
Protein Refseq | NP_005535 |
Uniprot ID | P35568 |
Chromosome Location | 2q36 |
Pathway | Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; |
Function | SH2 domain binding; insulin receptor binding; insulin-like growth factor receptor binding; insulin-like growth factor-activated receptor activity; phosphatidylinositol 3-kinase binding; |
◆ Recombinant Proteins | ||
IRS1-3212C | Recombinant Chicken IRS1 | +Inquiry |
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IRS1-1467H | Recombinant Human Insulin Receptor Substrate 1, GST-tagged | +Inquiry |
IRS1-3380H | Recombinant Human IRS1 Protein (Pro4-Arg267), N-His tagged | +Inquiry |
IRS1-4543H | Recombinant Human IRS1 protein, MBP&His-Avi-tagged, Biotinylated | +Inquiry |
◆ Cell & Tissue Lysates | ||
IRS1-872HCL | Recombinant Human IRS1 cell lysate | +Inquiry |
Not For Human Consumption!
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