Recombinant Human ISL1 Protein, GST-tagged
Cat.No. : | ISL1-5015H |
Product Overview : | Human ISL1 full-length ORF ( NP_002193.1, 1 a.a. - 346 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 65.1 kDa |
AA Sequence : | MGDPPKKKRLISLCVGCGNQIHDQY ILRVSPDLEWHAACLKCAECNQYLD ESCTCFVRDGKTYCKRDYIRLYGIK CAKCSIGFSKNDFVMRARSKVYHIE CFRCVACSRQLIPGDEFALREDGLF CRADHDVVERASLGAGDPLSPLHPA RPLQMAAEPISARQPALRPHVHKQP EKTTRVRTVLNEKQLHTLRTCYAAN PRPDALMKEQLVEMTGLSPRVIRVW FQNKRCKDKKRSIMMKQLQQQQPND KTNIQGMTGTPMVAASPERHDGGLQ ANPVEVQSYQPPWKVLSDFALQSDI DQPAFQQLVNFSEGGPGSNSTGSEV ASMSSQLPDTPNSMVASPIEA |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ISL1 ISL LIM homeobox 1 [ Homo sapiens ] |
Official Symbol : | ISL1 |
Synonyms : | ISL1; ISL LIM homeobox 1; ISL1 transcription factor, LIM/homeodomain, (islet 1); insulin gene enhancer protein ISL-1; Isl 1; ISLET1; islet-1; ISL1 transcription factor, LIM/homeodomain; Isl-1; |
Gene ID : | 3670 |
mRNA Refseq : | NM_002202 |
Protein Refseq : | NP_002193 |
MIM : | 600366 |
UniProt ID : | P61371 |
Products Types
◆ Recombinant Protein | ||
ISL1-2758R | Recombinant Rat ISL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ISL1-149H | Recombinant Human ISL1 Protein, T7/His/TEV-11R-tagged | +Inquiry |
ISL1-130H | Recombinant Human ISL1 protein, His-T7-tagged | +Inquiry |
ISL1-3120H | Recombinant Human ISL1 Protein (Met1-Ala349), N-His tagged | +Inquiry |
ISL1-129H | Recombinant Human ISL1 | +Inquiry |
◆ Lysates | ||
ISL1-5149HCL | Recombinant Human ISL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionISL1 protein is utilized in clinical research to better understand its role in development and disease, and to develop potential therapeutic interventions.
Yes, ISL1 protein has been implicated in various heart diseases, including congenital heart defects and cardiac regeneration.
Some preclinical studies are exploring the potential of targeting ISL1 protein for cardiac regeneration and treatment of heart disease.
Mutations in the ISL1 gene have been associated with certain congenital heart defects and developmental disorders.
Some research suggests a potential link between ISL1 protein and neurodegenerative diseases, but further studies are needed to establish a definitive connection.
Customer Reviews (3)
Write a reviewIts stability and purity make it an ideal candidate for studying protein structures at a high resolution, providing crucial insights into the organization and function of the ISL1 protein.
It has consistently demonstrated outstanding results, consistently producing clear and sharp bands, allowing for accurate and reliable protein detection and quantification.
I highly recommend the ISL1 protein for its exceptional performance in Western blot analysis.
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