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Recombinant Human ISL1 Protein, GST-tagged

Cat.No. : ISL1-5015H
Product Overview : Human ISL1 full-length ORF ( NP_002193.1, 1 a.a. - 346 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 65.1 kDa
AA Sequence : MGDPPKKKRLISLCVGCGNQIHDQY ILRVSPDLEWHAACLKCAECNQYLD ESCTCFVRDGKTYCKRDYIRLYGIK CAKCSIGFSKNDFVMRARSKVYHIE CFRCVACSRQLIPGDEFALREDGLF CRADHDVVERASLGAGDPLSPLHPA RPLQMAAEPISARQPALRPHVHKQP EKTTRVRTVLNEKQLHTLRTCYAAN PRPDALMKEQLVEMTGLSPRVIRVW FQNKRCKDKKRSIMMKQLQQQQPND KTNIQGMTGTPMVAASPERHDGGLQ ANPVEVQSYQPPWKVLSDFALQSDI DQPAFQQLVNFSEGGPGSNSTGSEV ASMSSQLPDTPNSMVASPIEA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ISL1 ISL LIM homeobox 1 [ Homo sapiens ]
Official Symbol : ISL1
Synonyms : ISL1; ISL LIM homeobox 1; ISL1 transcription factor, LIM/homeodomain, (islet 1); insulin gene enhancer protein ISL-1; Isl 1; ISLET1; islet-1; ISL1 transcription factor, LIM/homeodomain; Isl-1;
Gene ID : 3670
mRNA Refseq : NM_002202
Protein Refseq : NP_002193
MIM : 600366
UniProt ID : P61371

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is ISL1 protein utilized in clinical research? 03/16/2020

ISL1 protein is utilized in clinical research to better understand its role in development and disease, and to develop potential therapeutic interventions.

Are there any clinical implications of ISL1 protein in heart disease? 03/20/2019

Yes, ISL1 protein has been implicated in various heart diseases, including congenital heart defects and cardiac regeneration.

Are there any clinical trials targeting ISL1 protein for heart disease treatment? 12/16/2018

Some preclinical studies are exploring the potential of targeting ISL1 protein for cardiac regeneration and treatment of heart disease.

Are there any genetic disorders associated with ISL1 protein? 07/15/2018

Mutations in the ISL1 gene have been associated with certain congenital heart defects and developmental disorders.

Is there a link between ISL1 protein and neurodegenerative diseases? 02/21/2018

Some research suggests a potential link between ISL1 protein and neurodegenerative diseases, but further studies are needed to establish a definitive connection.

Customer Reviews (3)

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Reviews
12/31/2021

    Its stability and purity make it an ideal candidate for studying protein structures at a high resolution, providing crucial insights into the organization and function of the ISL1 protein.

    06/09/2020

      It has consistently demonstrated outstanding results, consistently producing clear and sharp bands, allowing for accurate and reliable protein detection and quantification.

      04/22/2019

        I highly recommend the ISL1 protein for its exceptional performance in Western blot analysis.

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