Recombinant Human ITCH protein
Cat.No. : | ITCH-01H |
Product Overview : | Recombinant Human ITCH protein was expressed in Bacterial. |
- Specification
- Gene Information
- Related Products
Description : | ITCH, also called atrophin-1 interacting protein 4 (AIP4), is a HECT-type E3 ubiquitin ligase. It contains an N-terminal Ca-dependent phospholipid-binding C2 domain, four WW domains, and a C-terminal HECT domain. Mice deficient in ITCH protein display many autoimmune-like disease characteristics such as lymphoproliferation in the spleen and lymph nodes. More than a dozen of substrates of ITCH have been identified including p63, p73 and Notch1. The ligase may be responsible for ubiquitinating proteins with K29-, K48-, and/or K63-linked ubiquitin chains. |
Source : | Bacterial |
Species : | Human |
Form : | 20 mM Tris, 150 mM NaCl, 2 mM Βme, 10% Glycerol. |
Molecular Mass : | 102.8 kDa |
Purity : | ~90% |
Storage : | Store at -80 centigrade; avoid multiple freeze-thaw cycles. |
Shipping : | Dry ice shipping |
Gene Name : | ITCH itchy E3 ubiquitin protein ligase [ Homo sapiens (human) ] |
Official Symbol : | ITCH |
Synonyms : | AIF4; AIP4; NAPP1; dJ468O1.1 |
Gene ID : | 83737 |
mRNA Refseq : | NM_001257137 |
Protein Refseq : | NP_001244066 |
MIM : | 606409 |
UniProt ID : | Q96J02 |
Products Types
◆ Recombinant Protein | ||
ITCH-5004H | Recombinant Human ITCH Protein, GST-tagged | +Inquiry |
ITCH-3094H | Recombinant Human ITCH protein | +Inquiry |
ITCH-8480Z | Recombinant Zebrafish ITCH | +Inquiry |
ITCH-1255H | Recombinant Human ITCH protein | +Inquiry |
◆ Lysates | ||
ITCH-5141HCL | Recombinant Human ITCH 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket