Species : |
Human |
Source : |
HEK293 |
Tag : |
Avi&His |
Protein Length : |
It contains Tyr 34 - Thr 977 (P13612) acidic tail& Glu20-His723 (P26010) basic tail. |
Description : |
Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. |
Form : |
Supplied as 0. 22um filtered solution in PBS (pH 7. 4). |
Molecular Mass : |
The protein has a predicted MW of 112. 5 kDa (P13612) & 81. 3 kDa (P26010). Due to glycosylation, the protein migrates to 70 kDa, 80 kDa and 130-150 kDa & 100-120 kDa based on Bis-Tris PAGE result |
Endotoxin : |
Less than 1EU per ug by the LAL method. |
Purity : |
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Storage : |
The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |