Recombinant Human ITGA5 Protein, GST-tagged
Cat.No. : | ITGA5-331H |
Product Overview : | Recombinant Human ITGA5(Phe42-Tyr995) fused with GST tag at N-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
Source : | HEK293 |
Species : | Human |
Tag : | GST |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2. |
Molecular Mass : | 105.1 kDa |
Protein length : | Phe42-Tyr995 |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Concentration : | Resuspend the protein to the desired concentration in proper buffer. |
Gene Name : | ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) [ Homo sapiens ] |
Official Symbol : | ITGA5 |
Synonyms : | ITGA5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); FNRA; integrin alpha-5; CD49e; VLA-5; integrin alpha-F; CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor, alpha subunit; very late activation protein 5, alpha subunit; VLA5A; |
Gene ID : | 3678 |
mRNA Refseq : | NM_002205 |
Protein Refseq : | NP_002196 |
MIM : | 135620 |
UniProt ID : | P08648 |
Products Types
◆ Recombinant Protein | ||
Itga5-1697R | Recombinant Rat Itga5 Protein, His-tagged | +Inquiry |
Itga5-3596M | Recombinant Mouse Itga5 Protein, Myc/DDK-tagged | +Inquiry |
ITGA5-078H | Recombinant Human ITGA5 Protein, C-His-tagged | +Inquiry |
ITGA5-4996H | Recombinant Human ITGA5 Protein | +Inquiry |
ITGA5-1211H | Recombinant Human ITGA5 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ITGA5-5132HCL | Recombinant Human ITGA5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionITGA5 works with extracellular matrix components, regulating cell-matrix interactions.
Altered ITGA5 activity can impact wound healing and tissue repair processes.
Genetic mutations in ITGA5 can lead to impaired cell adhesion and migration, affecting tissue integrity.
ITGA5, an integrin, is crucial for cell adhesion, facilitating cells' attachment to the extracellular matrix.
ITGA5 is involved in tissue remodeling, aiding in the reorganization and repair of tissues.
Targeting ITGA5 could offer new strategies for enhancing tissue repair and regeneration in various medical conditions.
It plays a key role in cell migration, essential for processes like wound healing and tissue formation.
Customer Reviews (3)
Write a reviewOutstanding accuracy, accelerates research progress.
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