Recombinant Human ITGA5 protein, His & GST-tagged
Cat.No. : | ITGA5-6771H |
Product Overview : | Recombinant Human ITGA5 aa. (Glu895~Ala1049 (Accession # P08648)) fused with N-terminal His & GST tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
Source : | E. coli |
Species : | Human |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 50.0kDa. |
Protein length : | Glu895~Ala1049 (Accession # P08648) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 8.4. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
Reconstitution : | Reconstitute in sterile ddH2O. |
Gene Name : | ITGA5 integrin subunit alpha 5 [ Homo sapiens (human) ] |
Official Symbol : | ITGA5 |
Synonyms : | FNRA; CD49e; VLA-5; VLA5A; CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); very late activation protein 5, alpha subunit; integrin alpha-5 |
Gene ID : | 3678 |
mRNA Refseq : | NM_002205.4 |
Protein Refseq : | NP_002196.4 |
UniProt ID : | P08648 |
Products Types
◆ Recombinant Protein | ||
ITGA5-4996H | Recombinant Human ITGA5 Protein | +Inquiry |
ITGA5-2341H | Recombinant Human ITGA5 Protein, His-tagged | +Inquiry |
ITGA5-4638M | Recombinant Mouse ITGA5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ITGA5-1211H | Recombinant Human ITGA5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Itga5-3596M | Recombinant Mouse Itga5 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
ITGA5-5132HCL | Recombinant Human ITGA5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionITGA5 works with extracellular matrix components, regulating cell-matrix interactions.
Altered ITGA5 activity can impact wound healing and tissue repair processes.
Genetic mutations in ITGA5 can lead to impaired cell adhesion and migration, affecting tissue integrity.
ITGA5, an integrin, is crucial for cell adhesion, facilitating cells' attachment to the extracellular matrix.
ITGA5 is involved in tissue remodeling, aiding in the reorganization and repair of tissues.
Targeting ITGA5 could offer new strategies for enhancing tissue repair and regeneration in various medical conditions.
It plays a key role in cell migration, essential for processes like wound healing and tissue formation.
Customer Reviews (3)
Write a reviewOutstanding accuracy, accelerates research progress.
Efficient service, essential for research outcomes.
Trusted for research integrity, an invaluable research asset.
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