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Recombinant Human ITGAL Protein, DYKDDDDK-tagged

Cat.No. : ITGAL-151H
Product Overview : Recombinant protein from the full-length sequence of Homo sapiens integrin subunit alpha L (ITGAL), transcript variant 1 (NM_002209), with a DYKDDDDK tag was expressed in human cell.
  • Specification
  • Gene Information
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Description : ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Source : Human cell
Species : Human
Tag : DYKDDDDK
Molecular Mass : 128.7 kDa
Endotoxin : < 0.1 ng/μg of protein (< 1 EU /μg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Storage Buffer : Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Gene Name : ITGAL integrin subunit alpha L [ Homo sapiens (human) ]
Official Symbol : ITGAL
Synonyms : ITGAL; integrin subunit alpha L; CD11A; LFA-1; LFA1A; integrin alpha-L; CD11 antigen-like family member A; LFA-1 alpha; LFA-1A; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; integrin gene promoter; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; lymphocyte function-associated antigen 1, alpha polypeptide
Gene ID : 3683
mRNA Refseq : NM_002209
Protein Refseq : NP_002200
MIM : 153370
UniProt ID : P20701

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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