Recombinant Human ITGAL Protein, His-tagged

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Recombinant Human ITGAL Protein, His-tagged

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Cat.No. : ITGAL-151H
Product Overview : Recombinant Human integrin subunit alpha L(ITGAL) protein, transcript variant 1(NM_002209), with a His tag, was expressed in human cells.
Description : ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Source : Human Cells
Species : Human
Tag : His
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.273, without any preservatives.
Molecular Mass : 126.1 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) [ Homo sapiens ]
Official Symbol : ITGAL
Synonyms : ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; integrin alpha-L; LFA 1; LFA-1A; LFA-1 alpha; integrin gene promoter; CD11 antigen-like family member A; lymphocyte function-associated antigen 1; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; LFA-1; LFA1A;
Gene ID : 3683
mRNA Refseq : NM_001114380
Protein Refseq : NP_001107852
MIM : 153370
UniProt ID : P20701
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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