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Recombinant Human ITGB1BP2 Protein, GST-tagged

Cat.No. : ITGB1BP2-4982H
Product Overview : Human ITGB1BP2 full-length ORF ( NP_036410.1, 1 a.a. - 347 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. [provided by RefSeq, May 2017]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 64.8 kDa
AA Sequence : MSLLCRNKGCGQHFDPNTNLPDSCC HHPGVPIFHDALKGWSCCRKRTVDF SEFLNIKGCTMGPHCAEKLPEAPQP EGPATSSSLQEQKPLNVIPKSAETL RRERPKSELPLKLLPLNISQALEMA LEQKELDQEPGAGLDSLIRTGSSCQ NPGCDAVYQGPESDATPCTYHPGAP RFHEGMKSWSCCGIQTLDFGAFLAQ PGCRVGRHDWGKQLPASCRHDWHQT DSLVVVTVYGQIPLPAFNWVKASQT ELHVHIVFDGNRVFQAQMKLWGVIN VEQSSVFLMPSRVEISLVKADPGSW AQLEHPDALAKKARAGVVLEMDEEE SDDSDDDLSWTEEEEEEEAMGE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ITGB1BP2 integrin beta 1 binding protein (melusin) 2 [ Homo sapiens ]
Official Symbol : ITGB1BP2
Synonyms : ITGB1BP2; integrin beta 1 binding protein (melusin) 2; integrin beta-1-binding protein 2; CHORDC3; ITGB1BP; MELUSIN; MSTP015; MGC119214;
Gene ID : 26548
mRNA Refseq : NM_012278
Protein Refseq : NP_036410
MIM : 300332
UniProt ID : Q9UKP3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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