| Description : |
This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
38.2 kDa |
| AA Sequence : |
MSLLCRNKGCGQHFDPNTNLPDSCC HHPGVPIFHDALKGWSCCRKRTVDF SEFLNIKGCTMGPHCAEKLPEAPQP EGPATSSSLQEQKPLNVIPKSAETL RRERPKSELPLKLLPLNISQALEMA LEQKELDQEPGAGLDSLIRTGSSCQ NPGCDAVYQGPESDATPCTYHPGAP RFHEGMKSWSCCGIQTLDFGAFLAQ PGCRVGRHDWGKQLPASCRHDWHQT DSLVVVTVYGQIPLPAFNWVKASQT ELHVHIVFDGNRVFQAQMKLWGVIN VEQSSVFLMPSRVEISLVKADPGSW AQLEHPDALAKKARAGVVLEMDEEE SDDSDDDLSWTEEEEEEEAMGETRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
