Recombinant Human ITGB2 protein, T7/His-tagged

• Cat.No.: ITGB2-181H
• Product Overview: Recombinant human CD18 cDNA (23 - 700 aa, derived from BC005861) protein fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: T7/His
• Form: 0.20 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQ GGEFELQECTKFKVSSCRECIESGP GCTWCQKLNFTGPGDPDSIRCDTRP QLLMRGCAADDIMDPTSLAETQEDH NGGQKQLSPQKVTLYLRPGQAAAFN VTFRRAKGYPIDLYYLMDLSYSMLD DLRNVKKLGGDLLRALNEITESGRI GFGSFVDKTVLPFVNTHPDKLRNPC PNKEKECQPPFAFRHVLKLTNNSNQ FQTEVGKQLISGNLDAPEGGLDAMM QVAACPEEIGWRNVTRLLVFATDDG FHFAGDGKLGAILTPNDGRCHLEDN LYKRSNEFDYPSVGQLAHKLAENNI QPIFAVTSRMVKTYEKLTEIIPKSA VGELSEDSSNVVHLIKNAYNKLSSR VFLDHNALPDTLKVTYDSFCSNGVT HRNQPRGDCDGVQINVPITFQVKVT ATECIQEQSFVIRALGFTDIVTVQV LPQCECRCRDQSRDRSLCHGKGFLE CGICRCDTGYIGKNCECQTQGRSSQ ELEGSCRKDNNSIICSGLGDCVCGQ CLCHTSDVPGKLIYGQYCECDTINC ERYNGQVCGGPGRGLCFCGKCRCHP GFEGSACQCERTTEGCLNPRRVECS GRGRCRCNVCECHSGYQLPLCQECP GCPSPCGKYISCAECLKFEKGPFGK NCSAACPGLQLSNNPVKGRTCKERD SEGCWVAYTLEQQDGMDRYLIYVDE SRECVAGPN
• Purity: >90% by SDS-PAGE.
• Storage: Keep at -80°C for long term storage. Product is stable at 4 °C for at least 30 days.

Gene Information

• Gene Name: ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) [ Homo sapiens ]
• Official Symbol: ITGB2
• Synonyms: ITGB2; integrin beta-2; LFA 1; MAC 1; integrin beta chain, beta 2; LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1
• Gene ID: 3689
• mRNA Refseq: NM_000211
• Protein Refseq: NP_000202
• MIM: 600065
• UniProt ID: P05107
• Chromosome Location: 21q22.3
• Pathway: Adaptive Immune System, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; CXCR3-mediated signaling events, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem
• Function: binding; glycoprotein binding; protein kinase binding; receptor activity