Recombinant Human ITK protein, Flag-tagged, Biotinylated

• Cat.No.: ITK-55H
• Product Overview: Recombinant Human ITK [2-620(end) amino acids of accession number NP_005537.3] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 75 kDa
• Purity: >90% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: ITK IL2-inducible T-cell kinase [ Homo sapiens ]
• Official Symbol: ITK
• Synonyms: ITK; IL2-inducible T-cell kinase; EMT; LYK; PSCTK2; kinase EMT; T-cell-specific kinase; tyrosine-protein kinase LYK
• Gene ID: 3702
• mRNA Refseq: NM_005546
• Protein Refseq: NP_005537
• MIM: 186973
• UniProt ID: Q08881
• Chromosome Location: 5q31-q32
• Pathway: Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class I PI3K signaling events, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; Generation of second messenger molecules, organism-specific biosystem
• Function: ATP binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding