Recombinant Human ITPKA Protein, MYC/DDK-tagged

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Recombinant Human ITPKA Protein, MYC/DDK-tagged

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Cat.No. : ITPKA-2641H
Product Overview : Recombinant Human ITPKA protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 50.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ITPKA inositol-trisphosphate 3-kinase A [ Homo sapiens ]
Official Symbol : ITPKA
Synonyms : IP3-3KA; IP3KA
Gene ID : 3706
mRNA Refseq : NM_002220
Protein Refseq : NP_002211
MIM : 147521
UniProt ID : P23677

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