Recombinant Human JAK3 Protein, His-tagged

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Recombinant Human JAK3 Protein, His-tagged

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Cat.No. : JAK3-467H
Product Overview : Recombinant human JAK3 (781-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.
Description : The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Source : Insect cells
Species : Human
Tag : His
Bio-activity : 252 nmol/min/mg
Molecular Mass : 40kDa
Purity : >80%
Stability : One year at -70 centigrade from the date of shipment.
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.2 μg/μL
Storage Buffer : Recombinant protein stored in PBS.
Shipping : Shipped on dry ice.
Sample Kinase Activity Plot :

The specific activity of JAK3 was determined to be 252 nmol/min/mg

Purity :

The purity was determined to be >80% by densitometry. Approx. MW 40kDa.

Gene Name : JAK3 Janus kinase 3 [ Homo sapiens (human) ]
Official Symbol : JAK3
Synonyms : JAK3; Janus kinase 3; JAKL; LJAK; JAK-3; L-JAK; tyrosine-protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); leukocyte Janus kinase; EC 2.7.10.2
Gene ID : 3718
mRNA Refseq : NM_000215
Protein Refseq : NP_000206
MIM : 600173
UniProt ID : P52333
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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