Recombinant Human JAK3 Protein, His-tagged
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Cat.No. : | JAK3-467H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human JAK3 (781-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. |
Description : | The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). |
Source : | Insect cells |
Species : | Human |
Tag : | His |
Bio-activity : | 252 nmol/min/mg |
Molecular Mass : | 40kDa |
Purity : | >80% |
Stability : | One year at -70 centigrade from the date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.2 μg/μL |
Storage Buffer : | Recombinant protein stored in PBS. |
Shipping : | Shipped on dry ice. |
Sample Kinase Activity Plot : |
![]() The specific activity of JAK3 was determined to be 252 nmol/min/mg |
Purity : |
![]() The purity was determined to be >80% by densitometry. Approx. MW 40kDa. |
Gene Name : | JAK3 Janus kinase 3 [ Homo sapiens (human) ] |
Official Symbol : | JAK3 |
Synonyms : | JAK3; Janus kinase 3; JAKL; LJAK; JAK-3; L-JAK; tyrosine-protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); leukocyte Janus kinase; EC 2.7.10.2 |
Gene ID : | 3718 |
mRNA Refseq : | NM_000215 |
Protein Refseq : | NP_000206 |
MIM : | 600173 |
UniProt ID : | P52333 |
◆ Recombinant Protein
Jak3-253M | Recombinant Mouse Jak3 Protein, His-tagged | +Inquiry |
JAK3-252H | Recombinant Human JAK3 Protein, His-tagged | +Inquiry |
JAK3-006H | Recombinant Human JAK3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
JAK3-3185H | Recombinant Human JAK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Jak3-3628M | Recombinant Mouse Jak3 Protein, Myc/DDK-tagged | +Inquiry |
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◆ Lysates
JAK3-5106HCL | Recombinant Human JAK3 293 Cell Lysate | +Inquiry |
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◆ Assay kits
Kit-1608 | JAK3 Activity Assay Kit | +Inquiry |
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