"JAK3" Related Products

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Recombinant Human JAK3 Protein, His-tagged

Cat.No. : JAK3-467H
Product Overview : Recombinant human JAK3 (781-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.
Description : The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Source : Insect cells
Species : Human
Tag : His
Bio-activity : 252 nmol/min/mg
Molecular Mass : 40kDa
Purity : >80%
Stability : One year at -70 centigrade from the date of shipment.
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.2 μg/μL
Storage Buffer : Recombinant protein stored in PBS.
Shipping : Shipped on dry ice.
Sample Kinase Activity Plot :

The specific activity of JAK3 was determined to be 252 nmol/min/mg

Purity :

The purity was determined to be >80% by densitometry. Approx. MW 40kDa.

Gene Name : JAK3 Janus kinase 3 [ Homo sapiens (human) ]
Official Symbol : JAK3
Synonyms : JAK3; Janus kinase 3; JAKL; LJAK; JAK-3; L-JAK; tyrosine-protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); leukocyte Janus kinase; EC 2.7.10.2
Gene ID : 3718
mRNA Refseq : NM_000215
Protein Refseq : NP_000206
MIM : 600173
UniProt ID : P52333

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