Recombinant Human JAK3 Protein, MYC/DDK-tagged, C13 and N15-labeled

Cat.No. : JAK3-006H
Product Overview : JAK3 MS Standard C13 and N15-labeled recombinant protein (NP_000206) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 124.9 kDa
AA Sequence : MAPPSEETPLIPQRSCSLLSTEAGA LHVLLPARGPGPPQRLSFSFGDHLA EDLCVQAAKASGILPVYHSLFALAT EDLSCWFPPSHIFSVEDASTQVLLY RIRFYFPNWFGLEKCHRFGLRKDLA SAILDLPVLEHLFAQHRSDLVSGRL PVGLSLKEQGECLSLAVLDLARMAR EQAQRPGELLKTVSYKACLPPSLRD LIQGLSFVTRRRIRRTVRRALRRVA ACQADRHSLMAKYIMDLERLDPAGA AETFHVGLPGALGGHDGLGLLRVAG DGGIAWTQGEQEVLQPFCDFPEIVD ISIKQAPRVGPAGEHRLVTVTRTDN QILEAEFPGLPEALSFVALVDGYFR LTTDSQHFFCKEVAPPRLLEEVAEQ CHGPITLDFAINKLKTGGSRPGSYV LRRSPQDFDSFLLTVCVQNPLGPDY KGCLIRRSPTGTFLLVGLSRPHSSL RELLATCWDGGLHVDGVAVTLTSCC IPRPKEKSNLIVVQRGHSPPTSSLV QPQSQYQLSQMTFHKIPADSLEWHE NLGHGSFTKIYRGCRHEVVDGEARK TEVLLKVMDAKHKNCMESFLEAASL MSQVSYRHLVLLHGVCMAGDSTMVQ EFVHLGAIDMYLRKRGHLVPASWKL QVVKQLAYALNYLEDKGLPHGNVSA RKVLLAREGADGSPPFIKLSDPGVS PAVLSLEMLTDRIPWVAPECLREAQ TLSLEADKWGFGATVWEVFSGVTMP ISALDPAKKLQFYEDRQQLPAPKWT ELALLIQQCMAYEPVQRPSFRAVIR DLNSLISSDYELLSDPTPGALAPRD GLWNGAQLYACQDPTIFEERHLKYI SQLGKGNFGSVELCRYDPLGDNTGA LVAVKQLQHSGPDQQRDFQREIQIL KALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDASR LLLYSSQICKGMEYLGSRRCVHRDL AARNILVESEAHVKIADFGLAKLLP LDKDYYVVREPGQSPIFWYAPESLS DNIFSRQSDVWSFGVVLYELFTYCD KSCSPSAEFLRMMGCERDVPALCRL LELLEEGQRLPAPPACPAEVHELMK LCWAPSPQDRPSFSALGPQLDMLWS GSRGCETHAFTAHPEGKHHSLSFST RTRPLEQKLISEEDLAANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : JAK3 Janus kinase 3 [ Homo sapiens (human) ]
Official Symbol : JAK3
Synonyms : JAK3; Janus kinase 3; JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK; tyrosine-protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); leukocyte Janus kinase; EC 2.7.10.2
Gene ID : 3718
mRNA Refseq : NM_000215
Protein Refseq : NP_000206
MIM : 600173
UniProt ID : P52333

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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