Recombinant Human JMJD1C Protein, His-SUMO/MYC-tagged
Cat.No. : | JMJD1C-1265H |
Product Overview : | Recombinant Human JMJD1C protein (2274-2498aa) was expressed in E. coli with N-terminal His-SUMO tag and C-terminal MYC tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO/MYC |
Form : | Tris-based buffer, 50% glycerol. |
Molecular Mass : | 45.5 kDa |
AA Sequence : | MPARYEDLLKSLPLPEYCNPEGKFN LASHLPGFFVRPDLGPRLCSAYGVV AAKDHDIGTTNLHIEVSDVV NILVYVGIAKGNGILSKAGILKKFE EEDLDDILRKRLKDSSEIPGALWHI YAGKDVDKIREFLQKISKEQ GLEVLPEHDPIRDQSWYVNKKLRQR LLEEYGVRTCTLIQFLGDAIVLPAG ALHQVQNFHSCIQVTEDFVS PEHLVESFHLTQELR |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Storage : | The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Gene Name : | JMJD1C jumonji domain containing 1C [ Homo sapiens (human) ] |
Official Symbol : | JMJD1C |
Synonyms : | KDM3C; TRIP8; TRIP-8; JMJD1C |
Gene ID : | 221037 |
mRNA Refseq : | NM_032776.2 |
Protein Refseq : | NP_116165.1 |
MIM : | 604503 |
UniProt ID : | Q15652 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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