Recombinant Human KCNH2-3C-eGFP Protein (M1-S1159 end, S631A, ΔP141-L380 and ΔS871-R1005), C-10×His-tagged

• Cat.No.: KCNH2-15H
• Product Overview: Recombinant human hERG(M1-S1159 end) (S631A) (ΔP141-L380 and ΔS871-R1005)-3C-EGFP-10His was expressed in mammalian cells.

Specification

• Description: This gene encodes a component of a voltage-activated potassium channel found in cardiac muscle, nerve cells, and microglia. Four copies of this protein interact with one copy of the KCNE2 protein to form a functional potassium channel. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.
• Source: Mammalian cell
• Species: Human
• Tag: C-10×His
• Form: Liquid
• Protein Length: M1-S1159 end, S631A, ΔP141-L380 and ΔS871-R1005
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50 mM Tris-HCl (pH 7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: KCNH2 potassium voltage-gated channel, subfamily H (eag-related), member 2 [ Homo sapiens (human) ]
• Official Symbol: KCNH2
• Synonyms: KCNH2; potassium voltage-gated channel, subfamily H (eag-related), member 2; LQT2; potassium voltage-gated channel subfamily H member 2; erg1; HERG; Kv11.1; ERG-1; H-ERG; hERG-1; eag homolog; eag-related protein 1; ether-a-go-go-related protein 1; ether-a-go-go-related gene potassium channel 1; voltage-gated potassium channel subunit Kv11.1; ether-a-go-go-related potassium channel protein; ERG1; SQT1; HERG1
• Gene ID: 3757
• mRNA Refseq: NM_000238
• Protein Refseq: NP_000229
• MIM: 152427
• UniProt ID: Q12809