Recombinant Human KCTD1 Protein, Myc/DDK-tagged, C13 and N15-labeled KCTD1-5494H

Specification Gene Information Related Products

Cat.No. :	KCTD1-5494H
Product Overview :	KCTD1 MS Standard C13 and N15-labeled recombinant protein (NP_945342) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation of Wnt signaling has been proposed in which the encoded protein enhances ubiquitination and degradation of the beta-catenin protein. Mutations in this gene have been identified in Scalp-ear-nipple (SEN) syndrome.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	29.4 kDa
AA Sequence :	MSRPLITRSP ASPLNNQGIP TPAQLTKSNA PVHIDVGGHM YTSSLATLTK YPESRIGRLF DGTEPIVLDS LKQHYFIDRD GQMFRYILNF LRTSKLLIPD DFKDYTLLYE EAKYFQLQPM LLEMERWKQD RETGRFSRPC ECLVVRVAPD LGERITLSGD KSLIEEVFPE IGDVMCNSVN AGWNHDSTHV IRFPLNGYCH LNSVQVLERL QQRGFEIVGS CGGGVDSSQF SEYVLRRELR RTPRVPSVIR IKQEPLDTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	KCTD1 potassium channel tetramerisation domain containing 1 [ Homo sapiens (human) ]
Official Symbol :	KCTD1
Synonyms :	KCTD1; potassium channel tetramerisation domain containing 1; C18orf5; BTB/POZ domain-containing protein KCTD1; potassium channel tetramerization domain-containing protein 1; DKFZp451C132;
Gene ID :	284252
mRNA Refseq :	NM_198991
Protein Refseq :	NP_945342
MIM :	613420
UniProt ID :	Q719H9