Recombinant Human KIDINS220, His-tagged

• Cat.No.: KIDINS220-26700TH
• Product Overview: Recombinant fragment, corresponding to amino acids 1604-1771 of Human Kidins220 with an N terminal His tag.MW 38 kDa

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1604-1771 a.a.
• Conjugation: HIS
• Tissue specificity: Abundant in developing and adult neural tissues as well as neuroendocrine cells and dendritic cells. Overexpressed in melanoma and melanoma cell lines.
• Form: Lyophilised:Reconstitute with 78 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: ADDSQLEKANLIELEDDSHSGKRGIPHSLSGLQDPIIARM SICSEDKKSPSECSLIASSPEENWPACQKAYNLNRTPS TVTLNNNSAPANRANQNFDEMEGIRETSQVILRPSSSP NPTTIQNENLKSMTHKRSQRSSYTRLSKDPPELHAAASSE STGFGEERESIL
• Sequence Similarities: Contains 12 ANK repeats.Contains 1 KAP NTPase domain.

Gene Information

• Gene Name: KIDINS220 kinase D-interacting substrate, 220kDa [ Homo sapiens ]
• Official Symbol: KIDINS220
• Synonyms: KIDINS220; kinase D-interacting substrate, 220kDa; kinase D-interacting substrate of 220 kDa; ankyrin repeat rich membrane spanning protein; ARMS
• Gene ID: 57498
• mRNA Refseq: NM_020738
• Protein Refseq: NP_065789
• Uniprot ID: Q9ULH0
• Chromosome Location: 2p24
• Pathway: ARMS-mediated activation, organism-specific biosystem; NGF signalling via TRKA from the plasma membrane, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem; Prolonged ERK activation events, organism-specific biosystem