Recombinant Human KIR2DL1 protein, His-Avi-tagged, Biotinylated

• Cat.No.: KIR2DL1-626HB
• Product Overview: Biotinylated Recombinant Human KIR2DL1 Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains His22-Arg242.

Specification

• Description: KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 27.1 KDa. Due to glycosylation, the protein migrates to 48-60KDa based on Bis-Tris PAGE result.
• Protein length: His22-Arg242
• Endotoxin: Less than 0.05EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: KIR2DL1
• Official Symbol: KIR2DL1
• Synonyms: CD158 antigen-like family member A; CD158a antigen; CD158a; CD158Ankat1; cl-42; killer cell immunoglobulin-like receptor 2DL1; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1; killer Ig receptor; killer inhibitory receptor 2-2-1; KIR221; KIR2DL1; MHC class I NK cell receptor; Natural killer-associated transcript 1; NKAT; NKAT-1; NKAT1KIR-K64; p58 killer cell inhibitory receptor KIR-K64; p58 natural killer cell receptor clones CL-42/47.11; p58 NK cell inhibitory receptor NKR-K6,47.11; p58 NK receptor CL-42/47.11; p58.1 MHC class-I-specific NK receptor; p58.1
• Gene ID: 3802
• mRNA Refseq: NM_014218.3
• Protein Refseq: NP_055033.2
• MIM: 604936
• UniProt ID: P43626