Active Recombinant Human KIR2DL2 protein, Fc-tagged

• Cat.No.: KIR2DL2-12H
• Product Overview: Recombinant Human KIR2DL2(His22 - His245) fused with Fc region of Human IgG1 at C-terminal was expressed in NS0.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: His22
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind HEK293T human embryonic kidney cells in a flow cytometry assay. When 1 μg of Recombinant Human KIR2DL2/CD158b1 Fc Chimera is added to 5 x 10^5 HEK293T cells, >20% of the cells will bind to the protein.
• Molecular Mass: Predicted Molecular Mass: 51.2 (monomer) kDa;SDS-PAGE: 65-75 kDa, reducing conditions.
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 100 μg/mL in PBS.

Gene Information

• Gene Name: KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 [ Homo sapiens ]
• Official Symbol: KIR2DL2
• Synonyms: KIR2DL2; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2; killer cell immunoglobulin-like receptor 2DL2; CD158B1; CD158k; cl 43; nkat6; NKAT-6; p58 NK receptor CL-43; MHC class I NK cell receptor; CD158 antigen-like family member B1; natural killer-associated transcript 6; p58 natural killer cell receptor clone CL-43; NKAT6; p58.2; CD158b
• Gene ID: 3803
• mRNA Refseq: NM_014219
• Protein Refseq: NP_055034
• MIM: 604937
• UniProt ID: P43627
• Chromosome Location: 19q13.4
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Graft-versus-host disease, organism-specific biosystem; Graft-versus-host disease, conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem
• Function: receptor activity